Midostaurin

Name: Midostaurin
Brand: Vaqora Chemicals
SKU: VQ-026688

About Midostaurin

Listed under CAS 120685-11-2, Midostaurin is a high-purity reference standard of Midostaurin available from Vaqora Chemicals. Its molecular formula is C35H30N4O4 and its molecular weight is 570.6 g/mol. Alternative names: N-Benzoylstaurosporine and PKC 412.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 8 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Midostaurin, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Midostaurin

View every impurity, metabolite and intermediate we list for Midostaurin.

Midostaurin impurities

Specifications & identifiers

Chemical identifiers
Product name	Midostaurin
Catalogue No.	VQ-026688
CAS Number	120685-11-2
IUPAC name	N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-N-methylbenzamide
Molecular formula	C₃₅H₃₀N₄O₄
Molecular weight	570.6 g/mol
Exact mass	570.2267
Grade	Reference Standard
HSN code	38229090
InChIKey	BMGQWWVMWDBQGC-IIFHNQTCSA-N
SMILES	C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
PubChem CID	9829523

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 4
TPSA	77.7 Å²
Synonyms	N-Benzoylstaurosporine, PKC 412, PKC-412, Benzoylstaurosporine, midostaurine, N-benzoyl-staurosporine, 4'-N-benzoyl staurosporine, 4'-N-Benzoylstaurosporine, Midostaurin (PKC412), PKC412 (Midostaurin), PKC-412 (Midostaurin)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation
H335May cause respiratory irritation
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P304 + P340, P305 + P351 + P338, P318, P319, P330, P337 + P317, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Midostaurin?

The CAS Registry Number of Midostaurin is 120685-11-2. It is also known as N-Benzoylstaurosporine, PKC 412, PKC-412.

What is the molecular formula and molecular weight of Midostaurin?

Midostaurin has the molecular formula C35H30N4O4 and a molecular weight of 570.6 g/mol.

What is Midostaurin used for?

Midostaurin is supplied as a characterised reference material related to Midostaurin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Midostaurin can I order?

We supply Midostaurin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Midostaurin?

Yes. Every lot of Midostaurin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Midostaurin be shipped internationally?

Yes. Midostaurin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.