Ribociclib WS

About Ribociclib WS

Ribociclib WS is a high-purity reference standard of Ribociclib carrying the CAS registry number 1211441-98-3. With the molecular formula C23H30N8O, it has a molar mass of 434.5 g/mol. Its systematic (IUPAC) name is 7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide. Alternative names: Ribociclib and LEE 011A.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Ribociclib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ribociclib WS is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ribociclib

View every impurity, metabolite and intermediate we list for Ribociclib.

Ribociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ribociclib WS
Catalogue No.	VQ-007711
CAS Number	1211441-98-3
Other CAS	1374639-75-4, 1374639-79-8
IUPAC name	7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide
Molecular formula	C₂₃H₃₀N₈O
Molecular weight	434.5 g/mol
Exact mass	434.2543
Grade	Reference Standard
HSN code	38229090
InChIKey	RHXHGRAEPCAFML-UHFFFAOYSA-N
SMILES	CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5
PubChem CID	44631912

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 7
TPSA	91.2 Å²
Synonyms	Ribociclib, LEE 011A, LEE-011, LEE011A, LEE-011A, Ribociclib (LEE011), LEE 011, 6ZZ, Ribociclib(LEE011), Ribociclib, LEE011, Ribociclib (Standard), LEE011 (Ribociclib)

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H360May damage fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P273, P280, P318, P319, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ribociclib WS?

The CAS Registry Number of Ribociclib WS is 1211441-98-3. It is also known as Ribociclib, LEE 011A, LEE-011.

What is the molecular formula and molecular weight of Ribociclib WS?

Ribociclib WS has the molecular formula C23H30N8O and a molecular weight of 434.5 g/mol. Its IUPAC name is 7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide.

What is Ribociclib WS used for?

Ribociclib WS is supplied as a characterised reference material related to Ribociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ribociclib WS can I order?

We supply Ribociclib WS in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ribociclib WS?

Yes. Every lot of Ribociclib WS is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ribociclib WS be shipped internationally?

Yes. Ribociclib WS is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.