Gemcitabine-13C-15N2

About Gemcitabine-13C-15N2

Gemcitabine-13C-15N2 is a stable isotope labelled analogue related to Gemcitabine carrying the CAS registry number 1233921-74-8. Formula C9H11F2N3O4, molecular weight 266.18 g/mol. Systematically, it is named 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl](213C,1,3-15N2)pyrimidin-2-one.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Gemcitabine

View every impurity, metabolite and intermediate we list for Gemcitabine.

Gemcitabine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Gemcitabine-13C-15N2
Catalogue No.	VQ-048514
CAS Number	1233921-74-8
IUPAC name	4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl](213C,1,3-15N2)pyrimidin-2-one
Molecular formula	C₉H₁₁F₂N₃O₄
Molecular weight	266.18 g/mol
Exact mass	266.0692
Grade	Reference Standard
HSN code	38229090
InChIKey	SDUQYLNIPVEERB-IETQKPOASA-N
SMILES	C1=C[15N]([13C](=O)[15N]=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F
PubChem CID	76973300

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.5
H-bond donors / acceptors	3 / 6
TPSA	108 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Gemcitabine-13C-15N2?

The CAS Registry Number of Gemcitabine-13C-15N2 is 1233921-74-8.

What is the molecular formula and molecular weight of Gemcitabine-13C-15N2?

Gemcitabine-13C-15N2 has the molecular formula C9H11F2N3O4 and a molecular weight of 266.18 g/mol. Its IUPAC name is 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl](213C,1,3-15N2)pyrimidin-2-one.

What is Gemcitabine-13C-15N2 used for?

Gemcitabine-13C-15N2 is supplied as a characterised reference material related to Gemcitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Gemcitabine-13C-15N2 can I order?

We supply Gemcitabine-13C-15N2 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Gemcitabine-13C-15N2?

Yes. Every lot of Gemcitabine-13C-15N2 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Gemcitabine-13C-15N2 be shipped internationally?

Yes. We export Gemcitabine-13C-15N2 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.