Dolutegravir oxidative degradation product B 1248263-78-6

About Dolutegravir oxidative degradation product B

Dolutegravir oxidative degradation product B is a metabolite or degradation product of Dolutegravir carrying the CAS registry number 1248263-78-6. Its molecular formula is C9H7F2NO3 and its molecular weight is 215.15 g/mol. Systematically, it is named 2-[(2,4-difluorophenyl)methylamino]-2-oxoacetic acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Dolutegravir, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Dolutegravir oxidative degradation product B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Dolutegravir

View every impurity, metabolite and intermediate we list for Dolutegravir.

Dolutegravir impurities

Specifications & identifiers

Chemical identifiers
Product name	Dolutegravir oxidative degradation product B
Catalogue No.	VQ-025360
CAS Number	1248263-78-6
IUPAC name	2-[(2,4-difluorophenyl)methylamino]-2-oxoacetic acid
Molecular formula	C₉H₇F₂NO₃
Molecular weight	215.15 g/mol
Exact mass	215.0394
Grade	Reference Standard
HSN code	38229090
InChIKey	YQDORBOSJQHAGW-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1F)F)CNC(=O)C(=O)O
PubChem CID	62229635

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	2 / 5
TPSA	66.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dolutegravir oxidative degradation product B?

The CAS Registry Number of Dolutegravir oxidative degradation product B is 1248263-78-6. It is also known as {[(2,4-difluorophenyl)methyl]carbamoyl}formic acid, 2-[[(2,4-Difluorophenyl)methyl]amino]-2-oxo-acetic acid, 2-((2,4-difluorobenzyl)amino)-2-oxoacetic acid.

What is the molecular formula and molecular weight of Dolutegravir oxidative degradation product B?

Dolutegravir oxidative degradation product B has the molecular formula C9H7F2NO3 and a molecular weight of 215.15 g/mol. Its IUPAC name is 2-[(2,4-difluorophenyl)methylamino]-2-oxoacetic acid.

What is Dolutegravir oxidative degradation product B used for?

Dolutegravir oxidative degradation product B is supplied as a characterised reference material related to Dolutegravir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dolutegravir oxidative degradation product B can I order?

We supply Dolutegravir oxidative degradation product B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dolutegravir oxidative degradation product B?

Yes. Every lot of Dolutegravir oxidative degradation product B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dolutegravir oxidative degradation product B be shipped internationally?

Yes. We export Dolutegravir oxidative degradation product B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.