Docetaxel EP Impurity G

About Docetaxel EP Impurity G

Docetaxel EP Impurity G is a pharmacopeial impurity of Docetaxel carrying the CAS registry number 125354-16-7. With the molecular formula C45H55NO15, it has a molar mass of 849.9 g/mol. Common synonyms include 10-Acetyl Docetaxel and Docetaxal.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Docetaxel to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Docetaxel EP Impurity G is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Docetaxel

View every impurity, metabolite and intermediate we list for Docetaxel.

Docetaxel impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Docetaxel EP Impurity G
Catalogue No.	VQ-022412
CAS Number	125354-16-7
IUPAC name	[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Molecular formula	C₄₅H₅₅NO₁₅
Molecular weight	849.9 g/mol
Exact mass	849.3572
Grade	Reference Standard
HSN code	38229090
InChIKey	LEMYAXKYCOBYOJ-OAGWZNDDSA-N
SMILES	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)OC(=O)C
PubChem CID	147895

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	4 / 15
TPSA	231 Å²
Synonyms	10-Acetyl Docetaxel, Docetaxal, N-Debenzoyl-N-(tert-butoxycarbonyl)taxol, 10-Acetyltaxotere, 10-Acetyldocetaxel

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Docetaxel EP Impurity G?

The CAS Registry Number of Docetaxel EP Impurity G is 125354-16-7. It is also known as 10-Acetyl Docetaxel, Docetaxal, N-Debenzoyl-N-(tert-butoxycarbonyl)taxol.

What is the molecular formula and molecular weight of Docetaxel EP Impurity G?

Docetaxel EP Impurity G has the molecular formula C45H55NO15 and a molecular weight of 849.9 g/mol.

What is Docetaxel EP Impurity G used for?

Docetaxel EP Impurity G is supplied as a characterised reference material related to Docetaxel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Docetaxel EP Impurity G can I order?

We supply Docetaxel EP Impurity G in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Docetaxel EP Impurity G?

Yes. Every lot of Docetaxel EP Impurity G is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Docetaxel EP Impurity G be shipped internationally?

Yes. We export Docetaxel EP Impurity G worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.