Papaverine EP Impurity A

About Papaverine EP Impurity A

Papaverine EP Impurity A is a pharmacopeial impurity of Papaverine carrying the CAS registry number 128-62-1. With the molecular formula C22H23NO7, it has a molar mass of 413.4 g/mol. It is also known as Noscapine or Papaverine Hydrochloride EP Impurity A.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Papaverine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Papaverine

View every impurity, metabolite and intermediate we list for Papaverine.

Papaverine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Papaverine EP Impurity A
Catalogue No.	VQ-034875
CAS Number	128-62-1
IUPAC name	(3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one
Molecular formula	C₂₂H₂₃NO₇
Molecular weight	413.4 g/mol
Exact mass	413.1475
Grade	Reference Standard
HSN code	38229090
InChIKey	AKNNEGZIBPJZJG-MSOLQXFVSA-N
SMILES	CN1CCC2=CC3=C(C(=C2[C@@H]1[C@@H]4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3
PubChem CID	275196

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	0 / 8
TPSA	75.7 Å²
Synonyms	Noscapine, Papaverine Hydrochloride EP Impurity A, Tusscapine, Methoxyhydrastine, Terbenol, Coscopin, Narcosine, Noscapalin, Longatin, Opianine, (-)-Narcotine, Narcotin

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Papaverine EP Impurity A?

The CAS Registry Number of Papaverine EP Impurity A is 128-62-1. It is also known as Noscapine, Papaverine Hydrochloride EP Impurity A, Tusscapine.

What is the molecular formula and molecular weight of Papaverine EP Impurity A?

Papaverine EP Impurity A has the molecular formula C22H23NO7 and a molecular weight of 413.4 g/mol. Its IUPAC name is (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one.

What is Papaverine EP Impurity A used for?

Papaverine EP Impurity A is supplied as a characterised reference material related to Papaverine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Papaverine EP Impurity A can I order?

We supply Papaverine EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Papaverine EP Impurity A?

Yes. Every lot of Papaverine EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Papaverine EP Impurity A be shipped internationally?

Yes. Papaverine EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.