Ambrisentan Impurity E

Name: Ambrisentan Impurity E
Brand: Vaqora Chemicals
SKU: VQ-021532

About Ambrisentan Impurity E

Ambrisentan Impurity E is an impurity of Ambrisentan carrying the CAS registry number 1312092-82-2. With the molecular formula C21H18N2O3, it has a molar mass of 346.4 g/mol. Its systematic (IUPAC) name is 2-(4,6-dimethylpyrimidin-2-yl)oxy-3,3-diphenylprop-2-enoic acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Ambrisentan, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ambrisentan Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ambrisentan

View every impurity, metabolite and intermediate we list for Ambrisentan.

Ambrisentan impurities

Specifications & identifiers

Chemical identifiers
Product name	Ambrisentan Impurity E
Catalogue No.	VQ-021532
CAS Number	1312092-82-2
IUPAC name	2-(4,6-dimethylpyrimidin-2-yl)oxy-3,3-diphenylprop-2-enoic acid
Molecular formula	C₂₁H₁₈N₂O₃
Molecular weight	346.4 g/mol
Exact mass	346.1317
Grade	Reference Standard
HSN code	38229090
InChIKey	RCXXMENQXDEDQY-UHFFFAOYSA-N
SMILES	CC1=CC(=NC(=N1)OC(=C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O)C
PubChem CID	54766127

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	1 / 5
TPSA	72.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ambrisentan Impurity E?

The CAS Registry Number of Ambrisentan Impurity E is 1312092-82-2. It is also known as 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3,3-diphenylacrylic acid, 2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3,3-diphenyl-2-propenoic Acid, 2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3,3-diphenyl-2-propenoicAcid.

What is the molecular formula and molecular weight of Ambrisentan Impurity E?

Ambrisentan Impurity E has the molecular formula C21H18N2O3 and a molecular weight of 346.4 g/mol. Its IUPAC name is 2-(4,6-dimethylpyrimidin-2-yl)oxy-3,3-diphenylprop-2-enoic acid.

What is Ambrisentan Impurity E used for?

Ambrisentan Impurity E is supplied as a characterised reference material related to Ambrisentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ambrisentan Impurity E can I order?

We supply Ambrisentan Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ambrisentan Impurity E?

Yes. Every lot of Ambrisentan Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ambrisentan Impurity E be shipped internationally?

Yes. We export Ambrisentan Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.