2-Acetylthiazole-4-carboxylic acid

Name: 2-Acetylthiazole-4-carboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-045084

About 2-Acetylthiazole-4-carboxylic acid

Vaqora Chemicals supplies 2-Acetylthiazole-4-carboxylic acid, an impurity of Tovorafenib registered under CAS number 13139-47-4. Its molecular formula is C6H5NO3S and its molecular weight is 171.18 g/mol. Systematically, it is named 2-acetyl-1,3-thiazole-4-carboxylic acid. It is also known as 4-Thiazolecarboxylic acid, 2-acetyl- or 2-Atca.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Tovorafenib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 2-Acetylthiazole-4-carboxylic acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tovorafenib

View every impurity, metabolite and intermediate we list for Tovorafenib.

Tovorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Acetylthiazole-4-carboxylic acid
Catalogue No.	VQ-045084
CAS Number	13139-47-4
IUPAC name	2-acetyl-1,3-thiazole-4-carboxylic acid
Molecular formula	C₆H₅NO₃S
Molecular weight	171.18 g/mol
Exact mass	170.999
Grade	Reference Standard
HSN code	38229090
InChIKey	SQOJCKCNKKLIFE-UHFFFAOYSA-N
SMILES	CC(=O)C1=NC(=CS1)C(=O)O
PubChem CID	193473

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	1 / 5
TPSA	95.5 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Acetylthiazole-4-carboxylic acid?

The CAS Registry Number of 2-Acetylthiazole-4-carboxylic acid is 13139-47-4. It is also known as 4-Thiazolecarboxylic acid, 2-acetyl-, 2-Atca.

What is the molecular formula and molecular weight of 2-Acetylthiazole-4-carboxylic acid?

2-Acetylthiazole-4-carboxylic acid has the molecular formula C6H5NO3S and a molecular weight of 171.18 g/mol. Its IUPAC name is 2-acetyl-1,3-thiazole-4-carboxylic acid.

What is 2-Acetylthiazole-4-carboxylic acid used for?

2-Acetylthiazole-4-carboxylic acid is supplied as a characterised reference material related to Tovorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Acetylthiazole-4-carboxylic acid can I order?

We supply 2-Acetylthiazole-4-carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Acetylthiazole-4-carboxylic acid?

Yes. Every lot of 2-Acetylthiazole-4-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Acetylthiazole-4-carboxylic acid be shipped internationally?

Yes. 2-Acetylthiazole-4-carboxylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.