ent-Entecavir-di-o-benzyl Ether

About ent-Entecavir-di-o-benzyl Ether

ent-Entecavir-di-o-benzyl Ether is an impurity of Entecavir carrying the CAS registry number 1354695-82-1. With the molecular formula C26H27N5O3, it has a molar mass of 457.5 g/mol. Its systematic (IUPAC) name is 2-amino-9-[(1R,3S,4R)-2-methylidene-4-phenylmethoxy-3-(phenylmethoxymethyl)cyclopentyl]-1H-purin-6-one.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Entecavir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, ent-Entecavir-di-o-benzyl Ether is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Entecavir

View every impurity, metabolite and intermediate we list for Entecavir.

Entecavir impurities

Specifications & identifiers

Chemical identifiers
Product name	ent-Entecavir-di-o-benzyl Ether
Catalogue No.	VQ-030495
CAS Number	1354695-82-1
IUPAC name	2-amino-9-[(1R,3S,4R)-2-methylidene-4-phenylmethoxy-3-(phenylmethoxymethyl)cyclopentyl]-1H-purin-6-one
Molecular formula	C₂₆H₂₇N₅O₃
Molecular weight	457.5 g/mol
Exact mass	457.2114
Grade	Reference Standard
HSN code	38229090
InChIKey	KROVOOOAPHSWCR-YPAWHYETSA-N
SMILES	C=C1[C@@H](C[C@H]([C@@H]1COCC2=CC=CC=C2)OCC3=CC=CC=C3)N4C=NC5=C4N=C(NC5=O)N
PubChem CID	137180883

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 5
TPSA	104 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of ent-Entecavir-di-o-benzyl Ether?

The CAS Registry Number of ent-Entecavir-di-o-benzyl Ether is 1354695-82-1.

What is the molecular formula and molecular weight of ent-Entecavir-di-o-benzyl Ether?

ent-Entecavir-di-o-benzyl Ether has the molecular formula C26H27N5O3 and a molecular weight of 457.5 g/mol. Its IUPAC name is 2-amino-9-[(1R,3S,4R)-2-methylidene-4-phenylmethoxy-3-(phenylmethoxymethyl)cyclopentyl]-1H-purin-6-one.

What is ent-Entecavir-di-o-benzyl Ether used for?

ent-Entecavir-di-o-benzyl Ether is supplied as a characterised reference material related to Entecavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of ent-Entecavir-di-o-benzyl Ether can I order?

We supply ent-Entecavir-di-o-benzyl Ether in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with ent-Entecavir-di-o-benzyl Ether?

Yes. Every lot of ent-Entecavir-di-o-benzyl Ether is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can ent-Entecavir-di-o-benzyl Ether be shipped internationally?

Yes. We export ent-Entecavir-di-o-benzyl Ether worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.