Captopril-d3

About Captopril-d3

Captopril-d3 is a stable isotope labelled analogue related to Captopril carrying the CAS registry number 1356383-38-4. The compound has the formula C9H15NO3S, corresponding to a molecular weight of 220.31 g/mol. Systematically, it is named (2S)-2,5,5-trideuterio-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid. Common synonyms include TMID-1136.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Captopril-d3 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Captopril

View every impurity, metabolite and intermediate we list for Captopril.

Captopril impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Captopril-d3
Catalogue No.	VQ-029628
CAS Number	1356383-38-4
IUPAC name	(2S)-2,5,5-trideuterio-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Molecular formula	C₉H₁₅NO₃S
Molecular weight	220.31 g/mol
Exact mass	220.0961
Grade	Reference Standard
HSN code	38229090
InChIKey	FAKRSMQSSFJEIM-SIHDFBQLSA-N
SMILES	[2H][C@]1(CCC(N1C(=O)[C@H](C)CS)([2H])[2H])C(=O)O
PubChem CID	71314500

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	2 / 4
TPSA	58.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Captopril-d3?

The CAS Registry Number of Captopril-d3 is 1356383-38-4. It is also known as TMID-1136, (S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic-2,5,5-d3 acid, (2S)-2,5,5-trideuterio-1-[(2S)-2-methyl-3-sulfanyl-propanoyl]pyrrolidine-2-carboxylic acid.

What is the molecular formula and molecular weight of Captopril-d3?

Captopril-d3 has the molecular formula C9H15NO3S and a molecular weight of 220.31 g/mol. Its IUPAC name is (2S)-2,5,5-trideuterio-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid.

What is Captopril-d3 used for?

Captopril-d3 is supplied as a characterised reference material related to Captopril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Captopril-d3 can I order?

We supply Captopril-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Captopril-d3?

Yes. Every lot of Captopril-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Captopril-d3 be shipped internationally?

Yes. We export Captopril-d3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.