Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandi… 13726-52-8

About Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate

Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate is an impurity of Methotrexate carrying the CAS registry number 13726-52-8. The compound has the formula C16H22N2O5, corresponding to a molecular weight of 322.36 g/mol. Its systematic (IUPAC) name is diethyl (2S)-2-[(4-aminobenzoyl)amino]pentanedioate. Common synonyms include Diethyl N-(4-aminobenzoyl)-L-glutamate and (S)-Diethyl 2-(4-aminobenzamido)pentanedioate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Methotrexate to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate
Catalogue No.	VQ-050305
CAS Number	13726-52-8
IUPAC name	diethyl (2S)-2-[(4-aminobenzoyl)amino]pentanedioate
Molecular formula	C₁₆H₂₂N₂O₅
Molecular weight	322.36 g/mol
Exact mass	322.1529
Grade	Reference Standard
HSN code	38229090
InChIKey	RJXFBLRRPYBPTM-ZDUSSCGKSA-N
SMILES	CCOC(=O)CC[C@@H](C(=O)OCC)NC(=O)C1=CC=C(C=C1)N
PubChem CID	73002

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	2 / 6
TPSA	108 Å²
Synonyms	N-(4-Aminobenzoyl)-L-glutamic acid diethyl ester, Diethyl N-(4-aminobenzoyl)-L-glutamate, L-Glutamic acid, N-(4-aminobenzoyl)-, 1,5-diethyl ester, (S)-Diethyl 2-(4-aminobenzamido)pentanedioate, 1,5-diethyl (2S)-2-[(4-aminophenyl)formamido]pentanedioate, diethyl (4-aminobenzoyl)-L-glutamate, L-Glutamic acid, N-(4-aminobenzoyl)-, diethyl ester, Diethyl N-(p-aminobenzoyl)-L-glutamate, 4-Abz-Glu(OEt)-OEt, N-(p-Aminobenzoyl)-L-glutamic acid diethyl ester, diethyl 4-aminobenzoyl-l-glutamate, diethyl p-aminobenzoyl-L-glutamate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate?

The CAS Registry Number of Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate is 13726-52-8. It is also known as N-(4-Aminobenzoyl)-L-glutamic acid diethyl ester, Diethyl N-(4-aminobenzoyl)-L-glutamate, L-Glutamic acid, N-(4-aminobenzoyl)-, 1,5-diethyl ester.

What is the molecular formula and molecular weight of Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate?

Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate has the molecular formula C16H22N2O5 and a molecular weight of 322.36 g/mol. Its IUPAC name is diethyl (2S)-2-[(4-aminobenzoyl)amino]pentanedioate.

What is Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate used for?

Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate can I order?

We supply Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate?

Yes. Every lot of Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate be shipped internationally?

Yes. We export Diethyl(2S)-2-[(4-aminobenzoyl)amino]pentandioate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.