Valsartan Methyl Ester

About Valsartan Methyl Ester

Valsartan Methyl Ester is a metabolite or degradation product of Valsartan carrying the CAS registry number 137863-17-3. With the molecular formula C25H31N5O3, it has a molar mass of 449.5 g/mol. The IUPAC name is methyl (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Valsartan, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Valsartan

View every impurity, metabolite and intermediate we list for Valsartan.

Valsartan impurities

Specifications & identifiers

Chemical identifiers
Product name	Valsartan Methyl Ester
Catalogue No.	VQ-028617
CAS Number	137863-17-3
IUPAC name	methyl (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate
Molecular formula	C₂₅H₃₁N₅O₃
Molecular weight	449.5 g/mol
Exact mass	449.2427
Grade	Reference Standard
HSN code	38229090
InChIKey	UJTNRXYTECQKFO-QHCPKHFHSA-N
SMILES	CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)OC
PubChem CID	11561462

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	1 / 6
TPSA	101 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H336May cause drowsiness or dizziness

Precautionary statements: P203, P261, P271, P280, P304 + P340, P318, P319, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Valsartan Methyl Ester?

The CAS Registry Number of Valsartan Methyl Ester is 137863-17-3. It is also known as methyl N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl}-L-valinate, Methyl N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valinate, N-[2-(1H-tetrazol-5-yl)biphenyl-4-yl methyl]-N-Valeryl-(L)-Valine methyl ester.

What is the molecular formula and molecular weight of Valsartan Methyl Ester?

Valsartan Methyl Ester has the molecular formula C25H31N5O3 and a molecular weight of 449.5 g/mol. Its IUPAC name is methyl (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate.

What is Valsartan Methyl Ester used for?

Valsartan Methyl Ester is supplied as a characterised reference material related to Valsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Valsartan Methyl Ester can I order?

We supply Valsartan Methyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Valsartan Methyl Ester?

Yes. Every lot of Valsartan Methyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Valsartan Methyl Ester be shipped internationally?

Yes. Valsartan Methyl Ester is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.