1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl… 137977-97-0

Name: 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one
Brand: Vaqora Chemicals
SKU: VQ-028452

About 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one

Listed under CAS 137977-97-0, 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one is an impurity of Tolvaptan available from Vaqora Chemicals. Formula C18H17ClN2O2, molecular weight 328.8 g/mol. Its systematic (IUPAC) name is 1-(4-amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-2H-1-benzazepin-5-one. Common synonyms include CS-B1535.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Tolvaptan impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tolvaptan

View every impurity, metabolite and intermediate we list for Tolvaptan.

Tolvaptan impurities

Specifications & identifiers

Chemical identifiers
Product name	1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one
Catalogue No.	VQ-028452
CAS Number	137977-97-0
IUPAC name	1-(4-amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-2H-1-benzazepin-5-one
Molecular formula	C₁₈H₁₇ClN₂O₂
Molecular weight	328.8 g/mol
Exact mass	328.0979
Grade	Reference Standard
HSN code	38229090
InChIKey	FLJCJPKXJWRZJB-UHFFFAOYSA-N
SMILES	CC1=C(C=CC(=C1)N)C(=O)N2CCCC(=O)C3=C2C=CC(=C3)Cl
PubChem CID	19608232

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	1 / 3
TPSA	63.4 Å²
Synonyms	1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one, 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one, 5H-1-Benzazepin-5-one, 1-(4-amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-, 1-(4-amino-2-methylbenzoyl)-7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine, 1-(4-amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one, CS-B1535, 1-(4-amino-2-methyl-benzoyl)-7-chloro-3,4-dihydro-2H-1-benzazepin-5-one, 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one?

The CAS Registry Number of 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one is 137977-97-0. It is also known as 1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one, 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one, 5H-1-Benzazepin-5-one, 1-(4-amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-.

What is the molecular formula and molecular weight of 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one?

1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one has the molecular formula C18H17ClN2O2 and a molecular weight of 328.8 g/mol. Its IUPAC name is 1-(4-amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-2H-1-benzazepin-5-one.

What is 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one used for?

1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one is supplied as a characterised reference material related to Tolvaptan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one can I order?

We supply 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one?

Yes. Every lot of 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one be shipped internationally?

Yes. We export 1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.