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API Process Intermediates & Related CompoundsReference StandardAvailable on request

4-Amino-6-chloropyrimidine-5-carbaldehyde

Synonyms: 4-Amino-6-chloro-5-pyrimidinecarboxaldehyde · 6-Chloro-5-difluoromethyl-pyrimidin-4-ylamine · 4-Amino-6-chloropyrimidine-5-carboxaldehyde · 5-Pyrimidinecarboxaldehyde, 4-amino-6-chloro-

CAS No.14160-93-1
FormulaC5H4ClN3O
Mol. weight157.56
Catalogue No.VQ-013081
PurityReference Standard
HSN2933

4-Amino-6-chloropyrimidine-5-carbaldehyde (CAS 14160-93-1) – Ruxolitinib intermediate. C5H4ClN3O, MW 157.56. Vaqora Chemicals: COA, global shipping.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
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16-section GHS SDS
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About 4-Amino-6-chloropyrimidine-5-carbaldehyde

Listed under CAS 14160-93-1, 4-Amino-6-chloropyrimidine-5-carbaldehyde is a process intermediate or related compound of Ruxolitinib available from Vaqora Chemicals. With the molecular formula C5H4ClN3O, it has a molar mass of 157.56 g/mol. Common synonyms include 4-Amino-6-chloro-5-pyrimidinecarboxaldehyde and 6-Chloro-5-difluoromethyl-pyrimidin-4-ylamine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Ruxolitinib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Amino-6-chloropyrimidine-5-carbaldehyde is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

  • API route development
  • Impurity fate & purge studies
  • Analytical method development

Industries

Related to Ruxolitinib

View every impurity, metabolite and intermediate we list for Ruxolitinib.

Ruxolitinib impurities

Specifications & identifiers

Chemical identifiers
Product name4-Amino-6-chloropyrimidine-5-carbaldehyde
Catalogue No.VQ-013081
CAS Number14160-93-1
IUPAC name4-amino-6-chloropyrimidine-5-carbaldehyde
Molecular formulaC5H4ClN3O
Molecular weight157.56 g/mol
Exact mass157.0043
GradeReference Standard
HSN code2933
InChIKeyGOJNFUXEBVBARW-UHFFFAOYSA-N
SMILESC1=NC(=C(C(=N1)Cl)C=O)N
PubChem CID84230
Physical properties
Physical formSolid
LogP (XLogP3)0.8
H-bond donors / acceptors1 / 4
TPSA68.9 Ų
Synonyms4-Amino-6-chloro-5-pyrimidinecarboxaldehyde, 6-Chloro-5-difluoromethyl-pyrimidin-4-ylamine, 4-Amino-6-chloropyrimidine-5-carboxaldehyde, 5-Pyrimidinecarboxaldehyde, 4-amino-6-chloro-, 4-Amino-6-chloro-5-pyrimidinecarbaldehyde, 6-amino-4-chloropyrimidine-5-carbaldehyde

Safety & hazard information (GHS)

GHS07 Harmful / irritant
Harmful / irritant

Signal word: Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of 4-Amino-6-chloropyrimidine-5-carbaldehyde?

The CAS Registry Number of 4-Amino-6-chloropyrimidine-5-carbaldehyde is 14160-93-1. It is also known as 4-Amino-6-chloro-5-pyrimidinecarboxaldehyde, 6-Chloro-5-difluoromethyl-pyrimidin-4-ylamine, 4-Amino-6-chloropyrimidine-5-carboxaldehyde.

What is the molecular formula and molecular weight of 4-Amino-6-chloropyrimidine-5-carbaldehyde?

4-Amino-6-chloropyrimidine-5-carbaldehyde has the molecular formula C5H4ClN3O and a molecular weight of 157.56 g/mol. Its IUPAC name is 4-amino-6-chloropyrimidine-5-carbaldehyde.

What is 4-Amino-6-chloropyrimidine-5-carbaldehyde used for?

4-Amino-6-chloropyrimidine-5-carbaldehyde is supplied as a characterised reference material related to Ruxolitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Amino-6-chloropyrimidine-5-carbaldehyde can I order?

We supply 4-Amino-6-chloropyrimidine-5-carbaldehyde in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Amino-6-chloropyrimidine-5-carbaldehyde?

Yes. Every lot of 4-Amino-6-chloropyrimidine-5-carbaldehyde is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Amino-6-chloropyrimidine-5-carbaldehyde be shipped internationally?

Yes. 4-Amino-6-chloropyrimidine-5-carbaldehyde is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

Enquire about 4-Amino-6-chloropyrimidine-5-carbaldehyde

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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