Nebivolol EP Impurity A

Name: Nebivolol EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-026844

About Nebivolol EP Impurity A

Vaqora Chemicals supplies Nebivolol EP Impurity A, a pharmacopeial impurity of Nebivolol registered under CAS number 1416402-13-5. The compound has the formula C22H26FNO4, corresponding to a molecular weight of 387.4 g/mol. Alternative names: rel-Desfluoro Nebivolol Impurity and Nebivolol Hydrochloride - Impurity A.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

This Nebivolol impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nebivolol EP Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Nebivolol

View every impurity, metabolite and intermediate we list for Nebivolol.

Nebivolol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nebivolol EP Impurity A
Catalogue No.	VQ-026844
CAS Number	1416402-13-5
IUPAC name	(1R)-2-[[(2R)-2-[(2R)-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
Molecular formula	C₂₂H₂₆FNO₄
Molecular weight	387.4 g/mol
Exact mass	387.1846
Grade	Reference Standard
HSN code	38229090
InChIKey	JMAVJQLYDMPPMQ-YHBROIRLSA-N
SMILES	C1CC2=CC=CC=C2O[C@H]1[C@@H](CNC[C@H]([C@@H]3CCC4=C(O3)C=CC(=C4)F)O)O
PubChem CID	172866581

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	3 / 6
TPSA	71 Å²
Synonyms	rel-Desfluoro Nebivolol Impurity, Nebivolol Hydrochloride - Impurity A, Nebivolol Impurity 33, Nebivolol Impurity 33(SR,RR), Desfluoro Nebivolol R,R,R,S Diastereomer, (R)-1-((R)-chroman-2-yl)-2-(((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nebivolol EP Impurity A?

The CAS Registry Number of Nebivolol EP Impurity A is 1416402-13-5. It is also known as rel-Desfluoro Nebivolol Impurity, Nebivolol Hydrochloride - Impurity A, Nebivolol Impurity 33.

What is the molecular formula and molecular weight of Nebivolol EP Impurity A?

Nebivolol EP Impurity A has the molecular formula C22H26FNO4 and a molecular weight of 387.4 g/mol. Its IUPAC name is (1R)-2-[[(2R)-2-[(2R)-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol.

What is Nebivolol EP Impurity A used for?

Nebivolol EP Impurity A is supplied as a characterised reference material related to Nebivolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nebivolol EP Impurity A can I order?

We supply Nebivolol EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nebivolol EP Impurity A?

Yes. Every lot of Nebivolol EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nebivolol EP Impurity A be shipped internationally?

Yes. We export Nebivolol EP Impurity A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.