DextroKetoconazole

Name: DextroKetoconazole
Brand: Vaqora Chemicals
SKU: VQ-037805

About DextroKetoconazole

DextroKetoconazole (CAS 142128-59-4) is an impurity of Ketoconazole offered by Vaqora Chemicals. Formula C26H28Cl2N4O4, molecular weight 531.4 g/mol. It is also known as (2R,4S)-ketoconazole or (+)-Ketoconazole.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Ketoconazole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies DextroKetoconazole in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ketoconazole

View every impurity, metabolite and intermediate we list for Ketoconazole.

Ketoconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	DextroKetoconazole
Catalogue No.	VQ-037805
CAS Number	142128-59-4
IUPAC name	1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
Molecular formula	C₂₆H₂₈Cl₂N₄O₄
Molecular weight	531.4 g/mol
Exact mass	530.1488
Grade	Reference Standard
HSN code	38229090
InChIKey	XMAYWYJOQHXEEK-OZXSUGGESA-N
SMILES	CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OC[C@H]3CO[C@](O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
PubChem CID	456201

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	0 / 6
TPSA	69.1 Å²
Synonyms	(2R,4S)-ketoconazole, (+)-Ketoconazole, (+)-(2R,4S)-Ketoconazole, Ketoconazole RS, Ketoconazole (k), Opera_ID_397, Ketoconazole, (2R,4S)-, US9138393, Ketoconozole, US9144538, Ketoconozole, US9150527, Ketoconazole, EI-107

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of DextroKetoconazole?

The CAS Registry Number of DextroKetoconazole is 142128-59-4. It is also known as (2R,4S)-ketoconazole, (+)-Ketoconazole, (+)-(2R,4S)-Ketoconazole.

What is the molecular formula and molecular weight of DextroKetoconazole?

DextroKetoconazole has the molecular formula C26H28Cl2N4O4 and a molecular weight of 531.4 g/mol. Its IUPAC name is 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone.

What is DextroKetoconazole used for?

DextroKetoconazole is supplied as a characterised reference material related to Ketoconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of DextroKetoconazole can I order?

We supply DextroKetoconazole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with DextroKetoconazole?

Yes. Every lot of DextroKetoconazole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can DextroKetoconazole be shipped internationally?

Yes. We export DextroKetoconazole worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.