3',5'-di-O-Benzyl Entecavir

About 3',5'-di-O-Benzyl Entecavir

3',5'-di-O-Benzyl Entecavir is an impurity of Entecavir carrying the CAS registry number 142217-81-0. Its molecular formula is C26H27N5O3 and its molecular weight is 457.5 g/mol. Systematically, it is named 2-amino-9-[(1S,3R,4S)-2-methylidene-4-phenylmethoxy-3-(phenylmethoxymethyl)cyclopentyl]-1H-purin-6-one. It is also known as Entecavir-9 or Entecavir Intermediate VIII Isomer.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Entecavir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3',5'-di-O-Benzyl Entecavir is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Entecavir

View every impurity, metabolite and intermediate we list for Entecavir.

Entecavir impurities

Specifications & identifiers

Chemical identifiers
Product name	3',5'-di-O-Benzyl Entecavir
Catalogue No.	VQ-030493
CAS Number	142217-81-0
IUPAC name	2-amino-9-[(1S,3R,4S)-2-methylidene-4-phenylmethoxy-3-(phenylmethoxymethyl)cyclopentyl]-1H-purin-6-one
Molecular formula	C₂₆H₂₇N₅O₃
Molecular weight	457.5 g/mol
Exact mass	457.2114
Grade	Reference Standard
HSN code	38229090
InChIKey	KROVOOOAPHSWCR-FKBYEOEOSA-N
SMILES	C=C1[C@H](C[C@@H]([C@H]1COCC2=CC=CC=C2)OCC3=CC=CC=C3)N4C=NC5=C4N=C(NC5=O)N
PubChem CID	135565404

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 5
TPSA	104 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3',5'-di-O-Benzyl Entecavir?

The CAS Registry Number of 3',5'-di-O-Benzyl Entecavir is 142217-81-0. It is also known as Entecavir-9, Entecavir Intermediate VIII Isomer, Dibenzyl Entecavir.

What is the molecular formula and molecular weight of 3',5'-di-O-Benzyl Entecavir?

3',5'-di-O-Benzyl Entecavir has the molecular formula C26H27N5O3 and a molecular weight of 457.5 g/mol. Its IUPAC name is 2-amino-9-[(1S,3R,4S)-2-methylidene-4-phenylmethoxy-3-(phenylmethoxymethyl)cyclopentyl]-1H-purin-6-one.

What is 3',5'-di-O-Benzyl Entecavir used for?

3',5'-di-O-Benzyl Entecavir is supplied as a characterised reference material related to Entecavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3',5'-di-O-Benzyl Entecavir can I order?

We supply 3',5'-di-O-Benzyl Entecavir in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3',5'-di-O-Benzyl Entecavir?

Yes. Every lot of 3',5'-di-O-Benzyl Entecavir is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3',5'-di-O-Benzyl Entecavir be shipped internationally?

Yes. We export 3',5'-di-O-Benzyl Entecavir worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.