Loperamide EP Impurity E

Name: Loperamide EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-022997

About Loperamide EP Impurity E

Vaqora Chemicals supplies Loperamide EP Impurity E, a pharmacopeial impurity of Loperamide registered under CAS number 1426322-82-8. Formula C38H40Cl2N2O3, molecular weight 643.6 g/mol. Systematically, it is named 1,4-bis[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutan-1-one. Alternative names: Loperamide hydrochloride EP Impurity E and Loperamide EP Impurity E (Free Base).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Loperamide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Loperamide EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Loperamide

View every impurity, metabolite and intermediate we list for Loperamide.

Loperamide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Loperamide EP Impurity E
Catalogue No.	VQ-022997
CAS Number	1426322-82-8
IUPAC name	1,4-bis[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutan-1-one
Molecular formula	C₃₈H₄₀Cl₂N₂O₃
Molecular weight	643.6 g/mol
Exact mass	642.2416
Grade	Reference Standard
HSN code	38229090
InChIKey	JQWKNSKWNAQZHW-UHFFFAOYSA-N
SMILES	C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCC(C3=CC=CC=C3)(C4=CC=CC=C4)C(=O)N5CCC(CC5)(C6=CC=C(C=C6)Cl)O
PubChem CID	71588005

Physical properties
Physical form	Solid
LogP (XLogP3)	6.8
H-bond donors / acceptors	2 / 4
TPSA	64 Å²
Synonyms	Loperamide hydrochloride EP Impurity E, Loperamide EP Impurity E (Free Base), Loperamide Impurity E, Loperamide - Impurity E, 1-Butanone, 1,4-bis(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-2,2-diphenyl-, 1,4-Bis[4-(4-chlorophenyl)-1-piperidinyl]-1-butanone Loperamide, 1,4-bis(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-2,2-diphenylbutan-1-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Loperamide EP Impurity E?

The CAS Registry Number of Loperamide EP Impurity E is 1426322-82-8. It is also known as Loperamide hydrochloride EP Impurity E, Loperamide EP Impurity E (Free Base), Loperamide Impurity E.

What is the molecular formula and molecular weight of Loperamide EP Impurity E?

Loperamide EP Impurity E has the molecular formula C38H40Cl2N2O3 and a molecular weight of 643.6 g/mol. Its IUPAC name is 1,4-bis[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutan-1-one.

What is Loperamide EP Impurity E used for?

Loperamide EP Impurity E is supplied as a characterised reference material related to Loperamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loperamide EP Impurity E can I order?

We supply Loperamide EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loperamide EP Impurity E?

Yes. Every lot of Loperamide EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loperamide EP Impurity E be shipped internationally?

Yes. We export Loperamide EP Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.