Axitinib Dimer Impurity 2

Name: Axitinib Dimer Impurity 2
Brand: Vaqora Chemicals
SKU: VQ-004463

About Axitinib Dimer Impurity 2

Listed under CAS 1428728-83-9, Axitinib Dimer Impurity 2 is an impurity of Axitinib available from Vaqora Chemicals with a typical assay of 95%. Formula C44H36N8O2S2, molecular weight 772.9 g/mol. Alternative names: Axitinib Dimer Impurity.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Axitinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 5 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Axitinib

View every impurity, metabolite and intermediate we list for Axitinib.

Axitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Axitinib Dimer Impurity 2
Catalogue No.	VQ-004463
CAS Number	1428728-83-9
IUPAC name	N-methyl-2-[[6-[3-[3-[2-(methylcarbamoyl)phenyl]sulfanyl-1H-indazol-6-yl]-2,4-dipyridin-2-ylcyclobutyl]-1H-indazol-3-yl]sulfanyl]benzamide
Molecular formula	C₄₄H₃₆N₈O₂S₂
Molecular weight	772.9 g/mol
Exact mass	772.2403
Grade	Reference Standard
Purity / assay	95%
HSN code	38229090
InChIKey	AMFHQHPHCWAIPO-UHFFFAOYSA-N
SMILES	CNC(=O)C1=CC=CC=C1SC2=NNC3=C2C=CC(=C3)C4C(C(C4C5=CC=CC=N5)C6=CC7=C(C=C6)C(=NN7)SC8=CC=CC=C8C(=O)NC)C9=CC=CC=N9
PubChem CID	169439210

Physical properties
Physical form	Solid
LogP (XLogP3)	7.5
H-bond donors / acceptors	4 / 8
TPSA	192 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Axitinib Dimer Impurity 2?

The CAS Registry Number of Axitinib Dimer Impurity 2 is 1428728-83-9. It is also known as Axitinib Dimer Impurity.

What is the molecular formula and molecular weight of Axitinib Dimer Impurity 2?

Axitinib Dimer Impurity 2 has the molecular formula C44H36N8O2S2 and a molecular weight of 772.9 g/mol. Its IUPAC name is N-methyl-2-[[6-[3-[3-[2-(methylcarbamoyl)phenyl]sulfanyl-1H-indazol-6-yl]-2,4-dipyridin-2-ylcyclobutyl]-1H-indazol-3-yl]sulfanyl]benzamide.

What is Axitinib Dimer Impurity 2 used for?

Axitinib Dimer Impurity 2 is supplied as a characterised reference material related to Axitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Axitinib Dimer Impurity 2 can I order?

We supply Axitinib Dimer Impurity 2 in Reference Standard (95%) grade, in 5 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Axitinib Dimer Impurity 2?

Yes. Every lot of Axitinib Dimer Impurity 2 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Axitinib Dimer Impurity 2 be shipped internationally?

Yes. Axitinib Dimer Impurity 2 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.