((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydrox… 143157-22-6

Name: ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate
Brand: Vaqora Chemicals
SKU: VQ-030968

About ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate

Vaqora Chemicals supplies ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate, a metabolite or degradation product of Gemcitabine registered under CAS number 143157-22-6. The compound has the formula C19H16F2O6, corresponding to a molecular weight of 378.3 g/mol. Systematically, it is named [(2R,3R)-3-benzoyloxy-4,4-difluoro-5-hydroxyoxolan-2-yl]methyl benzoate. Alternative names: 3,5-Dibenzoyl-DDFR.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Gemcitabine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Gemcitabine

View every impurity, metabolite and intermediate we list for Gemcitabine.

Gemcitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate
Catalogue No.	VQ-030968
CAS Number	143157-22-6
IUPAC name	[(2R,3R)-3-benzoyloxy-4,4-difluoro-5-hydroxyoxolan-2-yl]methyl benzoate
Molecular formula	C₁₉H₁₆F₂O₆
Molecular weight	378.3 g/mol
Exact mass	378.0915
Grade	Reference Standard
HSN code	38229090
InChIKey	PRZDMMRKPZAYHW-QOYAAKSSSA-N
SMILES	C1=CC=C(C=C1)C(=O)OC[C@@H]2[C@H](C(C(O2)O)(F)F)OC(=O)C3=CC=CC=C3
PubChem CID	11760620

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	1 / 8
TPSA	82.1 Å²
Synonyms	2-Deoxy-2,2-difluoro-D-ribofuranose-3,5-dibenzoate, 2-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate, D-erythro-Pentofuranose, 2-deoxy-2,2-difluoro-, 3,5-dibenzoate, (2R,3R)-2-[(benzoyloxy)methyl]-4,4-difluoro-5-hydroxyoxolan-3-yl benzoate, 3,5-Dibenzoyl-DDFR, 2-Deoxy-2,2-difluoro-d-erythropentofuranose 3,5-dibenzoate, (2R,3R)-2-((benzoyloxy)methyl)-4,4-difluoro-5-hydroxyoxolan-3-yl benzoate, 2-Deoxy-2,2-difluoro-D-ribofuranose 3,5-dibenzoate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate?

The CAS Registry Number of ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate is 143157-22-6. It is also known as 2-Deoxy-2,2-difluoro-D-ribofuranose-3,5-dibenzoate, 2-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate, D-erythro-Pentofuranose, 2-deoxy-2,2-difluoro-, 3,5-dibenzoate.

What is the molecular formula and molecular weight of ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate?

((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate has the molecular formula C19H16F2O6 and a molecular weight of 378.3 g/mol. Its IUPAC name is [(2R,3R)-3-benzoyloxy-4,4-difluoro-5-hydroxyoxolan-2-yl]methyl benzoate.

What is ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate used for?

((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate is supplied as a characterised reference material related to Gemcitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate can I order?

We supply ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate?

Yes. Every lot of ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate be shipped internationally?

Yes. We export ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl Benzoate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.