Fenebrutinib

Name: Fenebrutinib
Brand: Vaqora Chemicals
SKU: VQ-037614

About Fenebrutinib

Vaqora Chemicals supplies Fenebrutinib, a high-purity reference standard of Ibrutinib registered under CAS number 1434048-34-6. With the molecular formula C37H44N8O4, it has a molar mass of 664.8 g/mol. Alternative names: GDC-0853 and Bruton Tyrosine Kinase Inhibitor GDC-0853.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this Ibrutinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Fenebrutinib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ibrutinib

View every impurity, metabolite and intermediate we list for Ibrutinib.

Ibrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Fenebrutinib
Catalogue No.	VQ-037614
CAS Number	1434048-34-6
IUPAC name	10-[3-(hydroxymethyl)-4-[1-methyl-5-[[5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]-2-pyridinyl]amino]-6-oxo-3-pyridinyl]-2-pyridinyl]-4,4-dimethyl-1,10-diazatricyclo[6.4.0.02,6]dodeca-2(6),7-dien-9-one
Molecular formula	C₃₇H₄₄N₈O₄
Molecular weight	664.8 g/mol
Exact mass	664.3486
Grade	Reference Standard
HSN code	38229090
InChIKey	WNEODWDFDXWOLU-QHCPKHFHSA-N
SMILES	C[C@H]1CN(CCN1C2=CN=C(C=C2)NC3=CC(=CN(C3=O)C)C4=C(C(=NC=C4)N5CCN6C7=C(CC(C7)(C)C)C=C6C5=O)CO)C8COC8
PubChem CID	86567195

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	2 / 9
TPSA	119 Å²
Synonyms	GDC-0853, Bruton Tyrosine Kinase Inhibitor GDC-0853, Fenebrutinib (GDC-0853), GDC 0853, 9AJ, EX-A1308, RG-7845 (GDC-0853)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fenebrutinib?

The CAS Registry Number of Fenebrutinib is 1434048-34-6. It is also known as GDC-0853, Bruton Tyrosine Kinase Inhibitor GDC-0853, Fenebrutinib (GDC-0853).

What is the molecular formula and molecular weight of Fenebrutinib?

Fenebrutinib has the molecular formula C37H44N8O4 and a molecular weight of 664.8 g/mol.

What is Fenebrutinib used for?

Fenebrutinib is supplied as a characterised reference material related to Ibrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fenebrutinib can I order?

We supply Fenebrutinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fenebrutinib?

Yes. Every lot of Fenebrutinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fenebrutinib be shipped internationally?

Yes. We export Fenebrutinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.