4,6-Dichloro-5-nitro-2-propylthiopyrimidine 145783-14-8

Name: 4,6-Dichloro-5-nitro-2-propylthiopyrimidine
Brand: Vaqora Chemicals
SKU: VQ-028373

About 4,6-Dichloro-5-nitro-2-propylthiopyrimidine

4,6-Dichloro-5-nitro-2-propylthiopyrimidine is an impurity of Ticagrelor carrying the CAS registry number 145783-14-8. Formula C7H7Cl2N3O2S, molecular weight 268.12 g/mol. Systematically, it is named 4,6-dichloro-5-nitro-2-propylsulfanylpyrimidine. Alternative names: 4,6-Dichloro-5-nitro-2-(propythio)pyrimidine and CS-M1846.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Ticagrelor, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4,6-Dichloro-5-nitro-2-propylthiopyrimidine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ticagrelor

View every impurity, metabolite and intermediate we list for Ticagrelor.

Ticagrelor impurities

Specifications & identifiers

Chemical identifiers
Product name	4,6-Dichloro-5-nitro-2-propylthiopyrimidine
Catalogue No.	VQ-028373
CAS Number	145783-14-8
IUPAC name	4,6-dichloro-5-nitro-2-propylsulfanylpyrimidine
Molecular formula	C₇H₇Cl₂N₃O₂S
Molecular weight	268.12 g/mol
Exact mass	266.9636
Grade	Reference Standard
HSN code	38229090
InChIKey	DDEDQHVHVPJFAC-UHFFFAOYSA-N
SMILES	CCCSC1=NC(=C(C(=N1)Cl)[N+](=O)[O-])Cl
PubChem CID	22268924

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	0 / 5
TPSA	96.9 Å²
Synonyms	Pyrimidine, 4,6-dichloro-5-nitro-2-(propylthio)-, 4,6-Dichloro-5-nitro-2-(propythio)pyrimidine, 4,6-dichloro-5-nitro-2-(propylsulfanyl)pyrimidine, 4,6-dichloro-5-nitro-2-propylsulfanyl-pyrimidine, CS-M1846, 4,6-dichloro-5-nitro-2-(propylsulfanyl)pyri

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H311Toxic in contact with skin
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P260, P261, P262, P264, P264 + P265, P270, P272, P273, P280, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P361 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,6-Dichloro-5-nitro-2-propylthiopyrimidine?

The CAS Registry Number of 4,6-Dichloro-5-nitro-2-propylthiopyrimidine is 145783-14-8. It is also known as Pyrimidine, 4,6-dichloro-5-nitro-2-(propylthio)-, 4,6-Dichloro-5-nitro-2-(propythio)pyrimidine, 4,6-dichloro-5-nitro-2-(propylsulfanyl)pyrimidine.

What is the molecular formula and molecular weight of 4,6-Dichloro-5-nitro-2-propylthiopyrimidine?

4,6-Dichloro-5-nitro-2-propylthiopyrimidine has the molecular formula C7H7Cl2N3O2S and a molecular weight of 268.12 g/mol. Its IUPAC name is 4,6-dichloro-5-nitro-2-propylsulfanylpyrimidine.

What is 4,6-Dichloro-5-nitro-2-propylthiopyrimidine used for?

4,6-Dichloro-5-nitro-2-propylthiopyrimidine is supplied as a characterised reference material related to Ticagrelor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,6-Dichloro-5-nitro-2-propylthiopyrimidine can I order?

We supply 4,6-Dichloro-5-nitro-2-propylthiopyrimidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,6-Dichloro-5-nitro-2-propylthiopyrimidine?

Yes. Every lot of 4,6-Dichloro-5-nitro-2-propylthiopyrimidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,6-Dichloro-5-nitro-2-propylthiopyrimidine be shipped internationally?

Yes. 4,6-Dichloro-5-nitro-2-propylthiopyrimidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.