4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl… 146464-93-9

Name: 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid
Brand: Vaqora Chemicals
SKU: VQ-027563

About 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid

4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid is an impurity of Pralatrexate carrying the CAS registry number 146464-93-9. The compound has the formula C18H16N6O2, corresponding to a molecular weight of 348.4 g/mol. It is also known as CS-M1919.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 2 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Pralatrexate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Pralatrexate

View every impurity, metabolite and intermediate we list for Pralatrexate.

Pralatrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid
Catalogue No.	VQ-027563
CAS Number	146464-93-9
IUPAC name	4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoic acid
Molecular formula	C₁₈H₁₆N₆O₂
Molecular weight	348.4 g/mol
Exact mass	348.1335
Grade	Reference Standard
HSN code	38229090
InChIKey	YDEZNQPWTMVPCH-UHFFFAOYSA-N
SMILES	C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)O
PubChem CID	11002545

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	3 / 8
TPSA	141 Å²
Synonyms	10-Propargyl-4-deoxy-4-amino-10-deazapteroic Acid, Benzoic acid, 4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butynyl], Benzoic acid, 4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]-, 4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]Benzoic acid, 4-[1-[(2,4-Diamino-6-pteridinyl)methyl]-3-butynyl]benzoic acid, CS-M1919, 4-[1-[(2,4-diaminopteridin-6-yl)methyl]but-3-ynyl]benzoic acid

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H360May damage fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P316, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid?

The CAS Registry Number of 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid is 146464-93-9. It is also known as 10-Propargyl-4-deoxy-4-amino-10-deazapteroic Acid, Benzoic acid, 4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butynyl], Benzoic acid, 4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]-.

What is the molecular formula and molecular weight of 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid?

4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid has the molecular formula C18H16N6O2 and a molecular weight of 348.4 g/mol. Its IUPAC name is 4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoic acid.

What is 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid used for?

4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid is supplied as a characterised reference material related to Pralatrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid can I order?

We supply 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid?

Yes. Every lot of 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid be shipped internationally?

Yes. 4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.