Hydrocortisone EP Impurity G

Name: Hydrocortisone EP Impurity G
Brand: Vaqora Chemicals
SKU: VQ-022797

About Hydrocortisone EP Impurity G

Hydrocortisone EP Impurity G (CAS 14760-49-7) is a pharmacopeial impurity of Hydrocortisone offered by Vaqora Chemicals. With the molecular formula C21H28O5, it has a molar mass of 360.4 g/mol. It is also known as Hydrocortisone EP Impurity G (Free Base) or 21-Dehydrocortisol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Hydrocortisone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Hydrocortisone EP Impurity G
Catalogue No.	VQ-022797
CAS Number	14760-49-7
IUPAC name	2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoacetaldehyde
Molecular formula	C₂₁H₂₈O₅
Molecular weight	360.4 g/mol
Exact mass	360.1937
Grade	Reference Standard
HSN code	38229090
InChIKey	JIELFMXLFHFDRT-VWUMJDOOSA-N
SMILES	C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)C=O)O)C)O
PubChem CID	225755

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 5
TPSA	91.7 Å²
Synonyms	Hydrocortisone EP Impurity G (Free Base), 21-Dehydrocortisol, (11beta)-11,17-dihydroxy-3,20-dioxopregn-4-en-21-al, Pregn-4-en-21-al, 11,17-dihydroxy-3,20-dioxo-, (11beta)-, Hydrocortisone 21-Aldehyde Hydrate, 11beta,17-dihydroxy-21-oxoprogesterone, 4-pregnen-11beta,17alpha-diol-3,20-dione-21-al, 11beta,17alpha-dihydroxypregn-4-ene-3,20,21-trione, 11beta,17alpha-dihydroxypregn-4-en-3,20-dione-21-al, (11, A)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-al, (11I(2))-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-al

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydrocortisone EP Impurity G?

The CAS Registry Number of Hydrocortisone EP Impurity G is 14760-49-7. It is also known as Hydrocortisone EP Impurity G (Free Base), 21-Dehydrocortisol, (11beta)-11,17-dihydroxy-3,20-dioxopregn-4-en-21-al.

What is the molecular formula and molecular weight of Hydrocortisone EP Impurity G?

Hydrocortisone EP Impurity G has the molecular formula C21H28O5 and a molecular weight of 360.4 g/mol. Its IUPAC name is 2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoacetaldehyde.

What is Hydrocortisone EP Impurity G used for?

Hydrocortisone EP Impurity G is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydrocortisone EP Impurity G can I order?

We supply Hydrocortisone EP Impurity G in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydrocortisone EP Impurity G?

Yes. Every lot of Hydrocortisone EP Impurity G is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydrocortisone EP Impurity G be shipped internationally?

Yes. Hydrocortisone EP Impurity G is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.