Sacubitril Sodium

About Sacubitril Sodium

Sacubitril Sodium is a process intermediate or related compound of Sacubitril carrying the CAS registry number 149690-05-1. With the molecular formula C24H28NNaO5, it has a molar mass of 433.5 g/mol. The IUPAC name is sodium 4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate. Alternative names: Sacubitril sodium salt and AHU-377 sodium salt.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Sacubitril, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sacubitril Sodium is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	Sacubitril Sodium
Catalogue No.	VQ-013791
CAS Number	149690-05-1
Other CAS	149709-62-6, 1369773-39-6, 565453-99-8
IUPAC name	sodium 4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate
Molecular formula	C₂₄H₂₈NNaO₅
Molecular weight	433.5 g/mol
Exact mass	433.1865
Grade	Reference Standard
HSN code	2933
InChIKey	RRTBVEJIZWGATF-JKSHRDEXSA-M
SMILES	CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)[O-].[Na+]
PubChem CID	23707568

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 5
TPSA	95.5 Å²
Synonyms	Sacubitril sodium salt, AHU-377 sodium salt, Ahu-377 sodium, Sacubitril (sodium), AHU-377 (sodium), Sacubitril sodium?, ethyl (2R,4S)-5-{[1,1'-biphenyl]-4-yl}-2-methyl-4-[4-oxo-4-(sodiooxy)butanamido]pentanoate, Sodium 4-[[(2S,4R)-1-(4-Biphenylyl)-5-ethoxy-4-methyl-5-oxo-2-pentyl]amino]-4-oxobutanoate

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H332Harmful if inhaled
H361Suspected of damaging fertility or the unborn child
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P321, P330, P337 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sacubitril Sodium?

The CAS Registry Number of Sacubitril Sodium is 149690-05-1. It is also known as Sacubitril sodium salt, AHU-377 sodium salt, Ahu-377 sodium.

What is the molecular formula and molecular weight of Sacubitril Sodium?

Sacubitril Sodium has the molecular formula C24H28NNaO5 and a molecular weight of 433.5 g/mol. Its IUPAC name is sodium 4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate.

What is Sacubitril Sodium used for?

Sacubitril Sodium is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sacubitril Sodium can I order?

We supply Sacubitril Sodium in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sacubitril Sodium?

Yes. Every lot of Sacubitril Sodium is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sacubitril Sodium be shipped internationally?

Yes. Sacubitril Sodium is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.