Sacubitril Impurity 10
Synonyms: Ethyl (αR,γS)-γ-[[(1,1-dimethylethoxy)carbonyl]amino]-α-methyl[1,1′-biphenyl]-4-pentanoate · Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate · (2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate · (2R,4S)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid ethyl ester
Sacubitril Impurity 10 (CAS 149709-60-4) – Sacubitril impurity standard, 99%. C25H33NO4, MW 411.5. Request a quote: COA, bulk packs and worldwide export.
About Sacubitril Impurity 10
Vaqora Chemicals supplies Sacubitril Impurity 10, an impurity of Sacubitril registered under CAS number 149709-60-4 at a purity of 99%. With the molecular formula C25H33NO4, it has a molar mass of 411.5 g/mol. The IUPAC name is ethyl (2R,4S)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pentanoate. Alternative names: Valsartan Impurity 25 and LCZ-696 Impurity 50.
It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.
As a characterised impurity of Sacubitril, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sacubitril Impurity 10 is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Sacubitril.
Sacubitril impuritiesSpecifications & identifiers
| Product name | Sacubitril Impurity 10 |
|---|---|
| Catalogue No. | VQ-005856 |
| CAS Number | 149709-60-4 |
| IUPAC name | ethyl (2R,4S)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pentanoate |
| Molecular formula | C25H33NO4 |
| Molecular weight | 411.5 g/mol |
| Exact mass | 411.241 |
| Grade | Reference Standard |
| Purity / assay | 99% |
| HSN code | 38229090 |
| InChIKey | LMTIKWPJTDSUPT-GCJKJVERSA-N |
| SMILES | CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)OC(C)(C)C |
| PubChem CID | 58027501 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 5.7 |
| H-bond donors / acceptors | 1 / 4 |
| TPSA | 64.6 Ų |
| Synonyms | Ethyl (αR,γS)-γ-[[(1,1-dimethylethoxy)carbonyl]amino]-α-methyl[1,1′-biphenyl]-4-pentanoate, Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate, (2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate, (2R,4S)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid ethyl ester, Valsartan Impurity 25, Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoate, LCZ-696 Impurity 50 |
Documents
Frequently asked questions
What is the CAS number of Sacubitril Impurity 10?
The CAS Registry Number of Sacubitril Impurity 10 is 149709-60-4. It is also known as Ethyl (αR,γS)-γ-[[(1,1-dimethylethoxy)carbonyl]amino]-α-methyl[1,1′-biphenyl]-4-pentanoate, Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate, (2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate.
What is the molecular formula and molecular weight of Sacubitril Impurity 10?
Sacubitril Impurity 10 has the molecular formula C25H33NO4 and a molecular weight of 411.5 g/mol. Its IUPAC name is ethyl (2R,4S)-2-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(4-phenylphenyl)pentanoate.
What is Sacubitril Impurity 10 used for?
Sacubitril Impurity 10 is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Sacubitril Impurity 10 can I order?
We supply Sacubitril Impurity 10 in Reference Standard (99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Sacubitril Impurity 10?
Yes. Every lot of Sacubitril Impurity 10 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Sacubitril Impurity 10 be shipped internationally?
Yes. We export Sacubitril Impurity 10 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about Sacubitril Impurity 10
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