1'-Epi 2',2'-Difluoro-2'-deoxyuridine

Name: 1'-Epi 2',2'-Difluoro-2'-deoxyuridine
Brand: Vaqora Chemicals
SKU: VQ-030969

About 1'-Epi 2',2'-Difluoro-2'-deoxyuridine

Listed under CAS 153381-14-7, 1'-Epi 2',2'-Difluoro-2'-deoxyuridine is an impurity of Gemcitabine available from Vaqora Chemicals. Its molecular formula is C9H10F2N2O5 and its molecular weight is 264.18 g/mol. Its systematic (IUPAC) name is 1-[(2S,4S,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione. Alternative names: 2'-Deoxy-2',2'-difluoro-a-uridine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Gemcitabine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1'-Epi 2',2'-Difluoro-2'-deoxyuridine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Gemcitabine

View every impurity, metabolite and intermediate we list for Gemcitabine.

Gemcitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	1'-Epi 2',2'-Difluoro-2'-deoxyuridine
Catalogue No.	VQ-030969
CAS Number	153381-14-7
IUPAC name	1-[(2S,4S,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Molecular formula	C₉H₁₀F₂N₂O₅
Molecular weight	264.18 g/mol
Exact mass	264.0558
Grade	Reference Standard
HSN code	38229090
InChIKey	FIRDBEQIJQERSE-PIYBLCFFSA-N
SMILES	C1=CN(C(=O)NC1=O)[C@@H]2C([C@H]([C@H](O2)CO)O)(F)F
PubChem CID	71316352

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.3
H-bond donors / acceptors	3 / 7
TPSA	99.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1'-Epi 2',2'-Difluoro-2'-deoxyuridine?

The CAS Registry Number of 1'-Epi 2',2'-Difluoro-2'-deoxyuridine is 153381-14-7. It is also known as 2'-Deoxy-2',2'-difluoro-a-uridine, 1-(2-Deoxy-2,2-difluoro-alpha-D-threo-pentofuranosyl)pyrimidine-2,4(1H,3H)-dione.

What is the molecular formula and molecular weight of 1'-Epi 2',2'-Difluoro-2'-deoxyuridine?

1'-Epi 2',2'-Difluoro-2'-deoxyuridine has the molecular formula C9H10F2N2O5 and a molecular weight of 264.18 g/mol. Its IUPAC name is 1-[(2S,4S,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione.

What is 1'-Epi 2',2'-Difluoro-2'-deoxyuridine used for?

1'-Epi 2',2'-Difluoro-2'-deoxyuridine is supplied as a characterised reference material related to Gemcitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1'-Epi 2',2'-Difluoro-2'-deoxyuridine can I order?

We supply 1'-Epi 2',2'-Difluoro-2'-deoxyuridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1'-Epi 2',2'-Difluoro-2'-deoxyuridine?

Yes. Every lot of 1'-Epi 2',2'-Difluoro-2'-deoxyuridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1'-Epi 2',2'-Difluoro-2'-deoxyuridine be shipped internationally?

Yes. We export 1'-Epi 2',2'-Difluoro-2'-deoxyuridine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.