1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro… 1580889-33-3

Name: 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol
Brand: Vaqora Chemicals
SKU: VQ-023916

About 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol

Listed under CAS 1580889-33-3, 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol is an impurity of Tolvaptan available from Vaqora Chemicals. Its molecular formula is C25H23ClN2O3 and its molecular weight is 434.9 g/mol. Its systematic (IUPAC) name is N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]benzamide. Alternative names: Des-2-methylbenzoyl Tolvaptan and Desmethyl Tolvaptan.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Tolvaptan impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tolvaptan

View every impurity, metabolite and intermediate we list for Tolvaptan.

Tolvaptan impurities

Specifications & identifiers

Chemical identifiers
Product name	1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol
Catalogue No.	VQ-023916
CAS Number	1580889-33-3
IUPAC name	N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]benzamide
Molecular formula	C₂₅H₂₃ClN₂O₃
Molecular weight	434.9 g/mol
Exact mass	434.1397
Grade	Reference Standard
HSN code	38229090
InChIKey	LUMJRUXPFNZXRB-UHFFFAOYSA-N
SMILES	CC1=C(C=CC(=C1)NC(=O)C2=CC=CC=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)O
PubChem CID	71767691

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	2 / 3
TPSA	69.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol?

The CAS Registry Number of 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol is 1580889-33-3. It is also known as Des-2-methylbenzoyl Tolvaptan, Desmethyl Tolvaptan.

What is the molecular formula and molecular weight of 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol?

1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol has the molecular formula C25H23ClN2O3 and a molecular weight of 434.9 g/mol. Its IUPAC name is N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]benzamide.

What is 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol used for?

1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol is supplied as a characterised reference material related to Tolvaptan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol can I order?

We supply 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol?

Yes. Every lot of 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol be shipped internationally?

Yes. We export 1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.