10-Methyl Docetaxel

About 10-Methyl Docetaxel

10-Methyl Docetaxel is a process intermediate or related compound of Docetaxel carrying the CAS registry number 160084-81-1. The compound has the formula C44H55NO14, corresponding to a molecular weight of 821.9 g/mol. Alternative names: 7-Demethyl cabazitaxel.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

It is a process intermediate or related compound in the synthesis of Docetaxel, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 10-Methyl Docetaxel is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Docetaxel

View every impurity, metabolite and intermediate we list for Docetaxel.

Docetaxel impurities

Specifications & identifiers

Chemical identifiers
Product name	10-Methyl Docetaxel
Catalogue No.	VQ-048050
CAS Number	160084-81-1
IUPAC name	[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-12-methoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Molecular formula	C₄₄H₅₅NO₁₄
Molecular weight	821.9 g/mol
Exact mass	821.3623
HSN code	2933
InChIKey	KWXAADKMZIJIMH-BGKJQISDSA-N
SMILES	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)OC
PubChem CID	71722020

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	4 / 14
TPSA	213 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 10-Methyl Docetaxel?

The CAS Registry Number of 10-Methyl Docetaxel is 160084-81-1. It is also known as 7-Demethyl cabazitaxel.

What is the molecular formula and molecular weight of 10-Methyl Docetaxel?

10-Methyl Docetaxel has the molecular formula C44H55NO14 and a molecular weight of 821.9 g/mol.

What is 10-Methyl Docetaxel used for?

10-Methyl Docetaxel is supplied as a characterised reference material related to Docetaxel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 10-Methyl Docetaxel can I order?

We supply 10-Methyl Docetaxel, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 10-Methyl Docetaxel?

Yes. Every lot of 10-Methyl Docetaxel is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 10-Methyl Docetaxel be shipped internationally?

Yes. We export 10-Methyl Docetaxel worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.