Megestrol-d3

About Megestrol-d3

Megestrol-d3 is a stable isotope labelled analogue related to Medroxyprogesterone carrying the CAS registry number 162462-71-7. The compound has the formula C22H30O3, corresponding to a molecular weight of 345.5 g/mol. Alternative names: TMID-0128.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Medroxyprogesterone and related analytes in bioanalytical, pharmacokinetic and impurity studies. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Megestrol-d3 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Medroxyprogesterone

View every impurity, metabolite and intermediate we list for Medroxyprogesterone.

Medroxyprogesterone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Megestrol-d3
Catalogue No.	VQ-049029
CAS Number	162462-71-7
IUPAC name	(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-6-(trideuteriomethyl)-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₃₀O₃
Molecular weight	345.5 g/mol
Exact mass	345.2383
Grade	Reference Standard
HSN code	38229090
InChIKey	VXIMPSPISRVBPZ-QQLYPTFKSA-N
SMILES	[2H]C([2H])([2H])C1=C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)O)C)[C@@]4(C1=CC(=O)CC4)C
PubChem CID	169443162

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 3
TPSA	54.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Megestrol-d3?

The CAS Registry Number of Megestrol-d3 is 162462-71-7. It is also known as TMID-0128.

What is the molecular formula and molecular weight of Megestrol-d3?

Megestrol-d3 has the molecular formula C22H30O3 and a molecular weight of 345.5 g/mol. Its IUPAC name is (8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-6-(trideuteriomethyl)-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one.

What is Megestrol-d3 used for?

Megestrol-d3 is supplied as a characterised reference material related to Medroxyprogesterone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Megestrol-d3 can I order?

We supply Megestrol-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Megestrol-d3?

Yes. Every lot of Megestrol-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Megestrol-d3 be shipped internationally?

Yes. We export Megestrol-d3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.