Palbociclib-d8

About Palbociclib-d8

Palbociclib-d8 is a stable isotope labelled analogue related to Palbociclib carrying the CAS registry number 1628752-83-9. Formula C24H29N7O2, molecular weight 455.6 g/mol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Palbociclib and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Palbociclib-d8 is dispatched with a Certificate of Analysis (COA) to destinations worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Palbociclib

View every impurity, metabolite and intermediate we list for Palbociclib.

Palbociclib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Palbociclib-d8
Catalogue No.	VQ-041312
CAS Number	1628752-83-9
IUPAC name	6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7-one
Molecular formula	C₂₄H₂₉N₇O₂
Molecular weight	455.6 g/mol
Exact mass	455.2885
Grade	Reference Standard
HSN code	38229090
InChIKey	AHJRHEGDXFFMBM-PMCMNDOISA-N
SMILES	[2H]C1(C(N(C(C(N1)([2H])[2H])([2H])[2H])C2=CN=C(C=C2)NC3=NC=C4C(=C(C(=O)N(C4=N3)C5CCCC5)C(=O)C)C)([2H])[2H])[2H]
PubChem CID	76974685

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	2 / 8
TPSA	103 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Palbociclib-d8?

The CAS Registry Number of Palbociclib-d8 is 1628752-83-9.

What is the molecular formula and molecular weight of Palbociclib-d8?

Palbociclib-d8 has the molecular formula C24H29N7O2 and a molecular weight of 455.6 g/mol. Its IUPAC name is 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7-one.

What is Palbociclib-d8 used for?

Palbociclib-d8 is supplied as a characterised reference material related to Palbociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Palbociclib-d8 can I order?

We supply Palbociclib-d8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Palbociclib-d8?

Yes. Every lot of Palbociclib-d8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Palbociclib-d8 be shipped internationally?

Yes. We export Palbociclib-d8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.