Apalutamide-d4

Name: Apalutamide-d4
Brand: Vaqora Chemicals
SKU: VQ-029175

About Apalutamide-d4

Vaqora Chemicals supplies Apalutamide-d4, a stable isotope labelled analogue related to Apalutamide registered under CAS number 1638885-65-0. With the molecular formula C21H15F4N5O2S, it has a molar mass of 481.5 g/mol. Alternative names: TMIH-0093.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Apalutamide

View every impurity, metabolite and intermediate we list for Apalutamide.

Apalutamide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Apalutamide-d4
Catalogue No.	VQ-029175
CAS Number	1638885-65-0
IUPAC name	4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-1,1,3,3-tetradeuterio-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide
Molecular formula	C₂₁H₁₅F₄N₅O₂S
Molecular weight	481.5 g/mol
Exact mass	481.1134
Grade	Reference Standard
HSN code	38229090
InChIKey	HJBWBFZLDZWPHF-NZLXMSDQSA-N
SMILES	[2H]C1(CC(C12C(=O)N(C(=S)N2C3=CC(=C(C=C3)C(=O)NC)F)C4=CC(=C(N=C4)C#N)C(F)(F)F)([2H])[2H])[2H]
PubChem CID	86342611

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	1 / 9
TPSA	121 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Apalutamide-d4?

The CAS Registry Number of Apalutamide-d4 is 1638885-65-0. It is also known as TMIH-0093.

What is the molecular formula and molecular weight of Apalutamide-d4?

Apalutamide-d4 has the molecular formula C21H15F4N5O2S and a molecular weight of 481.5 g/mol. Its IUPAC name is 4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-1,1,3,3-tetradeuterio-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide.

What is Apalutamide-d4 used for?

Apalutamide-d4 is supplied as a characterised reference material related to Apalutamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Apalutamide-d4 can I order?

We supply Apalutamide-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Apalutamide-d4?

Yes. Every lot of Apalutamide-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Apalutamide-d4 be shipped internationally?

Yes. We export Apalutamide-d4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.