Loratadine EP Impurity E

Name: Loratadine EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-031622

About Loratadine EP Impurity E

Loratadine EP Impurity E (CAS 170727-59-0) is a pharmacopeial impurity of Loratadine offered by Vaqora Chemicals. The compound has the formula C22H23ClN2O2, corresponding to a molecular weight of 382.9 g/mol. It is also known as Loratadine - Impurity E or Isoloratadine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

This Loratadine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Loratadine EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Loratadine

View every impurity, metabolite and intermediate we list for Loratadine.

Loratadine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Loratadine EP Impurity E
Catalogue No.	VQ-031622
CAS Number	170727-59-0
IUPAC name	ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylate
Molecular formula	C₂₂H₂₃ClN₂O₂
Molecular weight	382.9 g/mol
Exact mass	382.1448
Grade	Reference Standard
HSN code	38229090
InChIKey	ZORGYPXITGWTSB-UHFFFAOYSA-N
SMILES	CCOC(=O)N1CCC(=CC1)C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl
PubChem CID	59047051

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	0 / 3
TPSA	42.4 Å²

Safety & hazard information (GHS)

Hazard statements

H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P273, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Loratadine EP Impurity E?

The CAS Registry Number of Loratadine EP Impurity E is 170727-59-0. It is also known as Loratadine - Impurity E, Isoloratadine, Iso Loratadine.

What is the molecular formula and molecular weight of Loratadine EP Impurity E?

Loratadine EP Impurity E has the molecular formula C22H23ClN2O2 and a molecular weight of 382.9 g/mol. Its IUPAC name is ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylate.

What is Loratadine EP Impurity E used for?

Loratadine EP Impurity E is supplied as a characterised reference material related to Loratadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loratadine EP Impurity E can I order?

We supply Loratadine EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loratadine EP Impurity E?

Yes. Every lot of Loratadine EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loratadine EP Impurity E be shipped internationally?

Yes. We export Loratadine EP Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.