Doxycycline Monohydrate

About Doxycycline Monohydrate

Doxycycline Monohydrate is a high-purity reference standard of Doxycycline carrying the CAS registry number 17086-28-1. Its molecular formula is C22H26N2O9 and its molecular weight is 462.4 g/mol. It is also known as Doxyhexal or Oracea.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Doxycycline, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Doxycycline Monohydrate is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Doxycycline

View every impurity, metabolite and intermediate we list for Doxycycline.

Doxycycline impurities

Specifications & identifiers

Chemical identifiers
Product name	Doxycycline Monohydrate
Catalogue No.	VQ-007439
CAS Number	17086-28-1
Other CAS	564-25-0
IUPAC name	(4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrate
Molecular formula	C₂₂H₂₆N₂O₉
Molecular weight	462.4 g/mol
Exact mass	462.1638
Grade	Reference Standard
HSN code	38229090
InChIKey	FZKWRPSUNUOXKJ-CVHRZJFOSA-N
SMILES	C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O
PubChem CID	54684461

Physical properties
Physical form	Solid
H-bond donors / acceptors	7 / 10
TPSA	183 Å²
Synonyms	Doxyhexal, Oracea, Vibravet, Invertin, Doxycycline hydrate, Doxycycline Hydrate (>90%), Supracyclin, Doxylin, Doxycycline (monohydrate), Vibramycin, Vibramycine, Vibramycin (TN)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H360May damage fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Doxycycline Monohydrate?

The CAS Registry Number of Doxycycline Monohydrate is 17086-28-1. It is also known as Doxyhexal, Oracea, Vibravet.

What is the molecular formula and molecular weight of Doxycycline Monohydrate?

Doxycycline Monohydrate has the molecular formula C22H26N2O9 and a molecular weight of 462.4 g/mol.

What is Doxycycline Monohydrate used for?

Doxycycline Monohydrate is supplied as a characterised reference material related to Doxycycline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Doxycycline Monohydrate can I order?

We supply Doxycycline Monohydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Doxycycline Monohydrate?

Yes. Every lot of Doxycycline Monohydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Doxycycline Monohydrate be shipped internationally?

Yes. Doxycycline Monohydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.