Tadalafil EP Impurity A

Name: Tadalafil EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-023823

About Tadalafil EP Impurity A

Tadalafil EP Impurity A (CAS 171596-27-3) is a pharmacopeial impurity of Tadalafil offered by Vaqora Chemicals. Formula C22H19N3O4, molecular weight 389.4 g/mol. It is also known as Tadalafil - Impurity A or Tadalafil, (6R,12AS)-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Tadalafil, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Tadalafil EP Impurity A is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Tadalafil

View every impurity, metabolite and intermediate we list for Tadalafil.

Tadalafil impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Tadalafil EP Impurity A
Catalogue No.	VQ-023823
CAS Number	171596-27-3
IUPAC name	(2R,8S)-2-(1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
Molecular formula	C₂₂H₁₉N₃O₄
Molecular weight	389.4 g/mol
Exact mass	389.1376
Grade	Reference Standard
HSN code	38229090
InChIKey	WOXKDUGGOYFFRN-HRAATJIYSA-N
SMILES	CN1CC(=O)N2[C@H](C1=O)CC3=C([C@H]2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36
PubChem CID	9821704

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 4
TPSA	74.9 Å²
Synonyms	Tadalafil - Impurity A, Tadalafil, (6R,12AS)-, Tadalafil specified impurity A, Tadalafil, (6R ,12aS)-, Tadalafil 6R ,12as diastereomer, 6R,12S-Tadalafil, Tadanafil Impurity A, (-)-Tadalafil 6R ,12as diastereomer, (6R ,12as)-tadalafil, Tadalafil IMpurity: IMpurity H, (6R,12aS)-, EX-A2848

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tadalafil EP Impurity A?

The CAS Registry Number of Tadalafil EP Impurity A is 171596-27-3. It is also known as Tadalafil - Impurity A, Tadalafil, (6R,12AS)-, Tadalafil specified impurity A.

What is the molecular formula and molecular weight of Tadalafil EP Impurity A?

Tadalafil EP Impurity A has the molecular formula C22H19N3O4 and a molecular weight of 389.4 g/mol. Its IUPAC name is (2R,8S)-2-(1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione.

What is Tadalafil EP Impurity A used for?

Tadalafil EP Impurity A is supplied as a characterised reference material related to Tadalafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tadalafil EP Impurity A can I order?

We supply Tadalafil EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tadalafil EP Impurity A?

Yes. Every lot of Tadalafil EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tadalafil EP Impurity A be shipped internationally?

Yes. Tadalafil EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.