(2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydro… 17447-35-7

Name: (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid
Brand: Vaqora Chemicals
SKU: VQ-048603

About (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid

(2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid is an impurity of Ibrutinib carrying the CAS registry number 17447-35-7. Formula C10H10ClNO5, molecular weight 259.64 g/mol. Systematically, it is named (2R,3R)-4-(4-chloroanilino)-2,3-dihydroxy-4-oxobutanoic acid. Common synonyms include (+)-4'-Chlorotartranilic acid and l-pcta.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Ibrutinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ibrutinib

View every impurity, metabolite and intermediate we list for Ibrutinib.

Ibrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	(2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid
Catalogue No.	VQ-048603
CAS Number	17447-35-7
IUPAC name	(2R,3R)-4-(4-chloroanilino)-2,3-dihydroxy-4-oxobutanoic acid
Molecular formula	C₁₀H₁₀ClNO₅
Molecular weight	259.64 g/mol
Exact mass	259.0248
Grade	Reference Standard
HSN code	38229090
InChIKey	JLBJYGCSAOHRPK-HTQZYQBOSA-N
SMILES	C1=CC(=CC=C1NC(=O)[C@@H]([C@H](C(=O)O)O)O)Cl
PubChem CID	2757916

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	4 / 5
TPSA	107 Å²
Synonyms	(+)-4'-Chlorotartranilic acid, Butanoic acid, 4-[(4-chlorophenyl)amino]-2,3-dihydroxy-4-oxo-, (2R,3R)-, l-pcta, 4-(4-Chloroanilino)-2,3-dihydroxy-4-oxobutanoic acid, L-Tartaric acid p-chloroanilide, (R,R)-4'-Chlorotartranilic acid, (R,R)-4'-Chloro-tartranilic acid, 4'-Chlorotartranilic acid, (R,R)-, 4'-Chlorotartranilic acid, (R,R)-rel-, (2R,3R)-4-(4-chloroanilino)-2,3-dihydroxy-4-oxo-butanoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid?

The CAS Registry Number of (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid is 17447-35-7. It is also known as (+)-4'-Chlorotartranilic acid, Butanoic acid, 4-[(4-chlorophenyl)amino]-2,3-dihydroxy-4-oxo-, (2R,3R)-, l-pcta.

What is the molecular formula and molecular weight of (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid?

(2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid has the molecular formula C10H10ClNO5 and a molecular weight of 259.64 g/mol. Its IUPAC name is (2R,3R)-4-(4-chloroanilino)-2,3-dihydroxy-4-oxobutanoic acid.

What is (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid used for?

(2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid is supplied as a characterised reference material related to Ibrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid can I order?

We supply (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid?

Yes. Every lot of (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid be shipped internationally?

Yes. (2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.