1-Bromo-2,3,4-trifluorobenzene

About 1-Bromo-2,3,4-trifluorobenzene

1-Bromo-2,3,4-trifluorobenzene is a process intermediate or related compound of Sitagliptin carrying the CAS registry number 176317-02-5. Formula C6H2BrF3, molecular weight 210.98 g/mol. Common synonyms include 2,3,4-Trifluorobromobenzene and Benzene, 1-bromo-2,3,4-trifluoro-.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Sitagliptin, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1-Bromo-2,3,4-trifluorobenzene is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Bromo-2,3,4-trifluorobenzene
Catalogue No.	VQ-012853
CAS Number	176317-02-5
IUPAC name	1-bromo-2,3,4-trifluorobenzene
Molecular formula	C₆H₂BrF₃
Molecular weight	210.98 g/mol
Exact mass	209.9292
Grade	Reference Standard
InChIKey	MUUAQFJJUGVBGB-UHFFFAOYSA-N
SMILES	C1=CC(=C(C(=C1F)F)F)Br
PubChem CID	2733255

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	0 / 3
TPSA	0 Å²
Synonyms	2,3,4-Trifluorobromobenzene, Benzene, 1-bromo-2,3,4-trifluoro-, trifluorophenyl bromide, l-bromo-2,3,4-trifluorobenzene, 1-bromo-2,3,4-trifluoro-benzene, Trifluorobromobenzene, 1-bromo-2,3,4trifluorobenzene, 2,3,4-Trifluoro Bromo Benzene, 4-bromo-1,2,3-trifluorobenzene, 1-Bromo-2,3,4-trifluorobenzene, 99%

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Bromo-2,3,4-trifluorobenzene?

The CAS Registry Number of 1-Bromo-2,3,4-trifluorobenzene is 176317-02-5. It is also known as 2,3,4-Trifluorobromobenzene, Benzene, 1-bromo-2,3,4-trifluoro-, trifluorophenyl bromide.

What is the molecular formula and molecular weight of 1-Bromo-2,3,4-trifluorobenzene?

1-Bromo-2,3,4-trifluorobenzene has the molecular formula C6H2BrF3 and a molecular weight of 210.98 g/mol. Its IUPAC name is 1-bromo-2,3,4-trifluorobenzene.

What is 1-Bromo-2,3,4-trifluorobenzene used for?

1-Bromo-2,3,4-trifluorobenzene is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Bromo-2,3,4-trifluorobenzene can I order?

We supply 1-Bromo-2,3,4-trifluorobenzene in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Bromo-2,3,4-trifluorobenzene?

Yes. Every lot of 1-Bromo-2,3,4-trifluorobenzene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Bromo-2,3,4-trifluorobenzene be shipped internationally?

Yes. 1-Bromo-2,3,4-trifluorobenzene is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.