Na-Boc-L-histidine

Name: Na-Boc-L-histidine
Brand: Vaqora Chemicals
SKU: VQ-038024

About Na-Boc-L-histidine

Na-Boc-L-histidine is an impurity of Histidine carrying the CAS registry number 17791-52-5. The compound has the formula C11H17N3O4, corresponding to a molecular weight of 255.27 g/mol. The IUPAC name is (2S)-3-(1H-imidazol-5-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid. It is also known as Boc-His-OH or tert-Butyloxycarbonyl-L-histidine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Histidine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Na-Boc-L-histidine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Histidine

View every impurity, metabolite and intermediate we list for Histidine.

Histidine impurities

Specifications & identifiers

Chemical identifiers
Product name	Na-Boc-L-histidine
Catalogue No.	VQ-038024
CAS Number	17791-52-5
IUPAC name	(2S)-3-(1H-imidazol-5-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
Molecular formula	C₁₁H₁₇N₃O₄
Molecular weight	255.27 g/mol
Exact mass	255.1219
Grade	Reference Standard
HSN code	38229090
InChIKey	AYMLQYFMYHISQO-QMMMGPOBSA-N
SMILES	CC(C)(C)OC(=O)N[C@@H](CC1=CN=CN1)C(=O)O
PubChem CID	87308

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	3 / 5
TPSA	104 Å²
Synonyms	Boc-His-OH, tert-Butyloxycarbonyl-L-histidine, Boc-L-Histidine, N-Boc-L-Histidine, L-Histidine, N-[(1,1-dimethylethoxy)carbonyl]-, Boc-His, N-tert-Butyloxycarbonyl-L-histidine, N-(tert-Butoxycarbonyl)-L-histidine, Nalpha-(tert-Butoxycarbonyl)-L-histidine, N-[(1,1-dimethylethoxy)carbonyl]-L-histidine, N-t-Butoxycarbonyl-(L)-histidine, Nalpha-boc-L-histidine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Na-Boc-L-histidine?

The CAS Registry Number of Na-Boc-L-histidine is 17791-52-5. It is also known as Boc-His-OH, tert-Butyloxycarbonyl-L-histidine, Boc-L-Histidine.

What is the molecular formula and molecular weight of Na-Boc-L-histidine?

Na-Boc-L-histidine has the molecular formula C11H17N3O4 and a molecular weight of 255.27 g/mol. Its IUPAC name is (2S)-3-(1H-imidazol-5-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid.

What is Na-Boc-L-histidine used for?

Na-Boc-L-histidine is supplied as a characterised reference material related to Histidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Na-Boc-L-histidine can I order?

We supply Na-Boc-L-histidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Na-Boc-L-histidine?

Yes. Every lot of Na-Boc-L-histidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Na-Boc-L-histidine be shipped internationally?

Yes. Na-Boc-L-histidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.