N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazo… 179552-75-1

Name: N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine
Brand: Vaqora Chemicals
SKU: VQ-035446

About N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine

Listed under CAS 179552-75-1, N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine is an impurity of Dacomitinib available from Vaqora Chemicals. Its molecular formula is C15H12ClFN4O and its molecular weight is 318.73 g/mol. Its systematic (IUPAC) name is 4-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Dacomitinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dacomitinib

View every impurity, metabolite and intermediate we list for Dacomitinib.

Dacomitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine
Catalogue No.	VQ-035446
CAS Number	179552-75-1
IUPAC name	4-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine
Molecular formula	C₁₅H₁₂ClFN₄O
Molecular weight	318.73 g/mol
Exact mass	318.0684
Grade	Reference Standard
HSN code	38229090
InChIKey	QRZFUQFQXCRJRR-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)N
PubChem CID	21847826

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	2 / 6
TPSA	73.1 Å²
Synonyms	N4-(3-chloro-4-fluorophenyl)-7-methoxy-4,6-quinazolinediamine, N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-aminoquinazolin-4-amine, 4,6-Quinazolinediamine, N4-(3-chloro-4-fluorophenyl)-7-methoxy-, 7-Methoxy-N4-(3-chloro-4-fluorophenyl)-4,6-quinazolinediamine, 6-amino4-(3-chloro-4-fluoroanilino)-7-methoxyquinazoline, 4-(3-chloro-4-fluorophenyl)amino-6-amino-7-methoxyquinazoline, 6-amino-4-(3-chloro-4-fluorophenylamino)-7-methoxy-quinazoline

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine?

The CAS Registry Number of N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine is 179552-75-1. It is also known as N4-(3-chloro-4-fluorophenyl)-7-methoxy-4,6-quinazolinediamine, N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-aminoquinazolin-4-amine, 4,6-Quinazolinediamine, N4-(3-chloro-4-fluorophenyl)-7-methoxy-.

What is the molecular formula and molecular weight of N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine?

N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine has the molecular formula C15H12ClFN4O and a molecular weight of 318.73 g/mol. Its IUPAC name is 4-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine.

What is N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine used for?

N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine is supplied as a characterised reference material related to Dacomitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine can I order?

We supply N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine?

Yes. Every lot of N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine be shipped internationally?

Yes. We export N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.