6-Hydroxy-7-methoxy-4(1H)-quinazolinone

Name: 6-Hydroxy-7-methoxy-4(1H)-quinazolinone
Brand: Vaqora Chemicals
SKU: VQ-030953

About 6-Hydroxy-7-methoxy-4(1H)-quinazolinone

6-Hydroxy-7-methoxy-4(1H)-quinazolinone is a metabolite or degradation product of Gefitinib carrying the CAS registry number 179688-52-9. With the molecular formula C9H8N2O3, it has a molar mass of 192.17 g/mol. Systematically, it is named 6-hydroxy-7-methoxy-3H-quinazolin-4-one. Common synonyms include 6-Hydroxy-7-methoxy-4(3H)-Quinazolinone and 6-Hydroxy-7-methoxyquinazolin-4(1H)-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Gefitinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 6-Hydroxy-7-methoxy-4(1H)-quinazolinone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Gefitinib

View every impurity, metabolite and intermediate we list for Gefitinib.

Gefitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Hydroxy-7-methoxy-4(1H)-quinazolinone
Catalogue No.	VQ-030953
CAS Number	179688-52-9
IUPAC name	6-hydroxy-7-methoxy-3H-quinazolin-4-one
Molecular formula	C₉H₈N₂O₃
Molecular weight	192.17 g/mol
Exact mass	192.0535
Grade	Reference Standard
HSN code	38229090
InChIKey	OKZIRNNFVQCDSA-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)N=CNC2=O)O
PubChem CID	135446413

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	2 / 4
TPSA	70.9 Å²
Synonyms	6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one, 6-Hydroxy-7-methoxy-4(3H)-Quinazolinone, 6-Hydroxy-7-methoxyquinazolin-4(1H)-one, 6-hydroxy-7-methoxyquinazolin-4(3H)-one, 6-hydroxy-7-methoxy-1H-quinazolin-4-one, 4(1H)-Quinazolinone, 6-hydroxy-7-methoxy-, 7-Methoxy-quinazoline-4,6-diol, 3,4-dihydro-4-oxo-6-hydroxy-7-methoxy-quinazoline, CS-B0939, 6-hydroxy-7-methoxyquinazoline-4(3H)-one, 6-hydroxy-7-methoxy-quinazolin-4(1h)-one, 6-hydroxy-7-(methyloxy)-4(1H)-quinazolinone

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Hydroxy-7-methoxy-4(1H)-quinazolinone?

The CAS Registry Number of 6-Hydroxy-7-methoxy-4(1H)-quinazolinone is 179688-52-9. It is also known as 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one, 6-Hydroxy-7-methoxy-4(3H)-Quinazolinone, 6-Hydroxy-7-methoxyquinazolin-4(1H)-one.

What is the molecular formula and molecular weight of 6-Hydroxy-7-methoxy-4(1H)-quinazolinone?

6-Hydroxy-7-methoxy-4(1H)-quinazolinone has the molecular formula C9H8N2O3 and a molecular weight of 192.17 g/mol. Its IUPAC name is 6-hydroxy-7-methoxy-3H-quinazolin-4-one.

What is 6-Hydroxy-7-methoxy-4(1H)-quinazolinone used for?

6-Hydroxy-7-methoxy-4(1H)-quinazolinone is supplied as a characterised reference material related to Gefitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Hydroxy-7-methoxy-4(1H)-quinazolinone can I order?

We supply 6-Hydroxy-7-methoxy-4(1H)-quinazolinone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Hydroxy-7-methoxy-4(1H)-quinazolinone?

Yes. Every lot of 6-Hydroxy-7-methoxy-4(1H)-quinazolinone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Hydroxy-7-methoxy-4(1H)-quinazolinone be shipped internationally?

Yes. 6-Hydroxy-7-methoxy-4(1H)-quinazolinone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.