Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate

Name: Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate
Brand: Vaqora Chemicals
SKU: VQ-050379

About Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate

Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate is a process intermediate or related compound of Palonosetron carrying the CAS registry number 1838-39-7. Formula C12H21NO4, molecular weight 243.3 g/mol. The IUPAC name is ethyl 1-(2-ethoxy-2-oxoethyl)piperidine-4-carboxylate. It is also known as 1-carbethoxymethyl-4-carbethoxypiperidine or Ethyl 1-ethoxycarbonylmethyl-iso-nipecotate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Palonosetron, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Palonosetron

View every impurity, metabolite and intermediate we list for Palonosetron.

Palonosetron impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate
Catalogue No.	VQ-050379
CAS Number	1838-39-7
IUPAC name	ethyl 1-(2-ethoxy-2-oxoethyl)piperidine-4-carboxylate
Molecular formula	C₁₂H₂₁NO₄
Molecular weight	243.3 g/mol
Exact mass	243.1471
HSN code	2933
InChIKey	OBXXSRPAQLOXJN-UHFFFAOYSA-N
SMILES	CCOC(=O)CN1CCC(CC1)C(=O)OCC
PubChem CID	74605

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	0 / 5
TPSA	55.8 Å²
Synonyms	1-carbethoxymethyl-4-carbethoxypiperidine, Ethyl 1-ethoxycarbonylmethyl-iso-nipecotate, 1-Piperidineacetic acid, 4-(ethoxycarbonyl)-, ethyl ester, Ethyl 1-(2-ethoxy-2-oxoethyl)-4-piperidinecarboxylate, Ethyl 1-(ethoxycarbonylmethyl)piperidine-4-carboxylate, 1-Piperidineacetic acid, 4-[ethoxycarbonyl]-, ethyl ester, ethyl 2-[4-(ethoxycarbonyl)piperidyl]acetate, ethyl 1-(2-ethoxy-2-oxo-ethyl)piperidine-4-carboxylate, Ethyl 1-Ethoxycarbonylmethyl Piperidine-4-Carboxylate, Ethyl 1-(2-ethoxy-2-oxoethyl)-4-piperidinecarboxylate #

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate?

The CAS Registry Number of Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate is 1838-39-7. It is also known as 1-carbethoxymethyl-4-carbethoxypiperidine, Ethyl 1-ethoxycarbonylmethyl-iso-nipecotate, 1-Piperidineacetic acid, 4-(ethoxycarbonyl)-, ethyl ester.

What is the molecular formula and molecular weight of Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate?

Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate has the molecular formula C12H21NO4 and a molecular weight of 243.3 g/mol. Its IUPAC name is ethyl 1-(2-ethoxy-2-oxoethyl)piperidine-4-carboxylate.

What is Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate used for?

Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate is supplied as a characterised reference material related to Palonosetron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate can I order?

We supply Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate?

Yes. Every lot of Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate be shipped internationally?

Yes. Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.