Gefitinib 3,4-Difluoro Impurity

Name: Gefitinib 3,4-Difluoro Impurity
Brand: Vaqora Chemicals
SKU: VQ-025967

About Gefitinib 3,4-Difluoro Impurity

Listed under CAS 184475-50-1, Gefitinib 3,4-Difluoro Impurity is an impurity of Gefitinib available from Vaqora Chemicals. The compound has the formula C22H24F2N4O3, corresponding to a molecular weight of 430.4 g/mol. Systematically, it is named N-(3,4-difluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine. Common synonyms include 3-Deschloro-3,4-Difluoro Gefitinib and Gefitinib Impurity TE.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Gefitinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Gefitinib

View every impurity, metabolite and intermediate we list for Gefitinib.

Gefitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Gefitinib 3,4-Difluoro Impurity
Catalogue No.	VQ-025967
CAS Number	184475-50-1
IUPAC name	N-(3,4-difluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
Molecular formula	C₂₂H₂₄F₂N₄O₃
Molecular weight	430.4 g/mol
Exact mass	430.1816
Grade	Reference Standard
HSN code	38229090
InChIKey	JACDFLVHUYYSBS-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)F)OCCCN4CCOCC4
PubChem CID	19077510

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	1 / 9
TPSA	68.7 Å²
Synonyms	N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine, 3-Deschloro-3,4-Difluoro Gefitinib, Gefitinib Impurity TE, Gefitinib impurity 02, 4-(3',4'-difluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)-quinazoline, 4-Quinazolinamine, N-(3,4-difluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-, N-(3,4-Difluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Gefitinib 3,4-Difluoro Impurity?

The CAS Registry Number of Gefitinib 3,4-Difluoro Impurity is 184475-50-1. It is also known as N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine, 3-Deschloro-3,4-Difluoro Gefitinib, Gefitinib Impurity TE.

What is the molecular formula and molecular weight of Gefitinib 3,4-Difluoro Impurity?

Gefitinib 3,4-Difluoro Impurity has the molecular formula C22H24F2N4O3 and a molecular weight of 430.4 g/mol. Its IUPAC name is N-(3,4-difluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine.

What is Gefitinib 3,4-Difluoro Impurity used for?

Gefitinib 3,4-Difluoro Impurity is supplied as a characterised reference material related to Gefitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Gefitinib 3,4-Difluoro Impurity can I order?

We supply Gefitinib 3,4-Difluoro Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Gefitinib 3,4-Difluoro Impurity?

Yes. Every lot of Gefitinib 3,4-Difluoro Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Gefitinib 3,4-Difluoro Impurity be shipped internationally?

Yes. We export Gefitinib 3,4-Difluoro Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.