Defluoro Dolutegravir

Name: Defluoro Dolutegravir
Brand: Vaqora Chemicals
SKU: VQ-013349

About Defluoro Dolutegravir

Defluoro Dolutegravir (CAS 1863916-88-4) is a process intermediate or related compound of Dolutegravir offered by Vaqora Chemicals. The compound has the formula C20H20FN3O5, corresponding to a molecular weight of 401.4 g/mol. Common synonyms include 4-Fluoro Dolutegravir and Defluoro Dolutegravir (above 85%).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Process chemists and analysts use it when developing synthetic routes to Dolutegravir, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Defluoro Dolutegravir in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Dolutegravir

View every impurity, metabolite and intermediate we list for Dolutegravir.

Dolutegravir impurities

Specifications & identifiers

Chemical identifiers
Product name	Defluoro Dolutegravir
Catalogue No.	VQ-013349
CAS Number	1863916-88-4
IUPAC name	(3S,7R)-N-[(4-fluorophenyl)methyl]-11-hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide
Molecular formula	C₂₀H₂₀FN₃O₅
Molecular weight	401.4 g/mol
Exact mass	401.1387
Grade	Reference Standard
HSN code	2933
InChIKey	WINWILCOHJPYNO-ABAIWWIYSA-N
SMILES	C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=CC=C(C=C4)F)O
PubChem CID	139025689

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	2 / 7
TPSA	99.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Defluoro Dolutegravir?

The CAS Registry Number of Defluoro Dolutegravir is 1863916-88-4. It is also known as 4-Fluoro Dolutegravir, Defluoro Dolutegravir (>85%).

What is the molecular formula and molecular weight of Defluoro Dolutegravir?

Defluoro Dolutegravir has the molecular formula C20H20FN3O5 and a molecular weight of 401.4 g/mol. Its IUPAC name is (3S,7R)-N-[(4-fluorophenyl)methyl]-11-hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide.

What is Defluoro Dolutegravir used for?

Defluoro Dolutegravir is supplied as a characterised reference material related to Dolutegravir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Defluoro Dolutegravir can I order?

We supply Defluoro Dolutegravir in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Defluoro Dolutegravir?

Yes. Every lot of Defluoro Dolutegravir is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Defluoro Dolutegravir be shipped internationally?

Yes. We export Defluoro Dolutegravir worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.