Sofosbuvir-d6

About Sofosbuvir-d6

Sofosbuvir-d6 is a stable isotope labelled analogue related to Sofosbuvir carrying the CAS registry number 1868135-06-1. With the molecular formula C22H29FN3O9P, it has a molar mass of 535.5 g/mol. Alternative names: GS-7977 D6.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Sofosbuvir and related analytes in bioanalytical, pharmacokinetic and impurity studies. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Sofosbuvir

View every impurity, metabolite and intermediate we list for Sofosbuvir.

Sofosbuvir impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Sofosbuvir-d6
Catalogue No.	VQ-033904
CAS Number	1868135-06-1
IUPAC name	1,1,1,3,3,3-hexadeuteriopropan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
Molecular formula	C₂₂H₂₉FN₃O₉P
Molecular weight	535.5 g/mol
Exact mass	535.2002
Grade	Reference Standard
HSN code	38229090
InChIKey	TTZHDVOVKQGIBA-FMYNZQRGSA-N
SMILES	[2H]C([2H])([2H])C(C([2H])([2H])[2H])OC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3
PubChem CID	92044384

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	3 / 11
TPSA	153 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sofosbuvir-d6?

The CAS Registry Number of Sofosbuvir-d6 is 1868135-06-1. It is also known as GS-7977 D6.

What is the molecular formula and molecular weight of Sofosbuvir-d6?

Sofosbuvir-d6 has the molecular formula C22H29FN3O9P and a molecular weight of 535.5 g/mol.

What is Sofosbuvir-d6 used for?

Sofosbuvir-d6 is supplied as a characterised reference material related to Sofosbuvir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sofosbuvir-d6 can I order?

We supply Sofosbuvir-d6 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sofosbuvir-d6?

Yes. Every lot of Sofosbuvir-d6 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sofosbuvir-d6 be shipped internationally?

Yes. We export Sofosbuvir-d6 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.