4-Hydroxy Valsartan

About 4-Hydroxy Valsartan

4-Hydroxy Valsartan is a metabolite or degradation product of Valsartan carrying the CAS registry number 188259-69-0. With the molecular formula C24H29N5O4, it has a molar mass of 451.5 g/mol. The IUPAC name is (2S)-2-[4-hydroxypentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-3-methylbutanoic acid. It is also known as Valery 4-Hydroxy Valsartan or Valeryl-4-hydroxyvalsartan.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Valsartan, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 4-Hydroxy Valsartan in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Valsartan

View every impurity, metabolite and intermediate we list for Valsartan.

Valsartan impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxy Valsartan
Catalogue No.	VQ-028618
CAS Number	188259-69-0
IUPAC name	(2S)-2-[4-hydroxypentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-3-methylbutanoic acid
Molecular formula	C₂₄H₂₉N₅O₄
Molecular weight	451.5 g/mol
Exact mass	451.222
Grade	Reference Standard
HSN code	38229090
InChIKey	ICSQZMPILLPFKC-XLDIYJRPSA-N
SMILES	CC(C)[C@@H](C(=O)O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(=O)CCC(C)O
PubChem CID	9911647

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	3 / 7
TPSA	132 Å²
Synonyms	Valery 4-Hydroxy Valsartan, Valeryl-4-hydroxyvalsartan, L-Valine, N-(4-hydroxy-1-oxopentyl)-N-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, (S)-N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-valine, L-Valine, N-(4-hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxy Valsartan?

The CAS Registry Number of 4-Hydroxy Valsartan is 188259-69-0. It is also known as Valery 4-Hydroxy Valsartan, Valeryl-4-hydroxyvalsartan, L-Valine, N-(4-hydroxy-1-oxopentyl)-N-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-.

What is the molecular formula and molecular weight of 4-Hydroxy Valsartan?

4-Hydroxy Valsartan has the molecular formula C24H29N5O4 and a molecular weight of 451.5 g/mol. Its IUPAC name is (2S)-2-[4-hydroxypentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-3-methylbutanoic acid.

What is 4-Hydroxy Valsartan used for?

4-Hydroxy Valsartan is supplied as a characterised reference material related to Valsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxy Valsartan can I order?

We supply 4-Hydroxy Valsartan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxy Valsartan?

Yes. Every lot of 4-Hydroxy Valsartan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxy Valsartan be shipped internationally?

Yes. We export 4-Hydroxy Valsartan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.