Ruxolitinib Impurity-H

Name: Ruxolitinib Impurity-H
Brand: Vaqora Chemicals
SKU: VQ-005848

About Ruxolitinib Impurity-H

Ruxolitinib Impurity-H (CAS 191605-10-4) is an impurity of Ruxolitinib offered by Vaqora Chemicals. Its molecular formula is C20H18O10 and its molecular weight is 418.3 g/mol. The IUPAC name is (2S,3S)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid. Common synonyms include Di(+)-(p-anisoyl)-D-tartrate and (2S,3S)-(+)-Di(p-anisoyl)tartaric acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Ruxolitinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ruxolitinib Impurity-H in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ruxolitinib

View every impurity, metabolite and intermediate we list for Ruxolitinib.

Ruxolitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ruxolitinib Impurity-H
Catalogue No.	VQ-005848
CAS Number	191605-10-4
IUPAC name	(2S,3S)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid
Molecular formula	C₂₀H₁₈O₁₀
Molecular weight	418.3 g/mol
Exact mass	418.09
Grade	Reference Standard
HSN code	38229090
InChIKey	KWWCVCFQHGKOMI-HOTGVXAUSA-N
SMILES	COC1=CC=C(C=C1)C(=O)O[C@@H]([C@@H](C(=O)O)OC(=O)C2=CC=C(C=C2)OC)C(=O)O
PubChem CID	9810979

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	2 / 10
TPSA	146 Å²
Synonyms	Di(+)-(p-anisoyl)-D-tartrate, (2S,3S)-2,3-bis((4-methoxybenzoyl)oxy)succinic acid, (2S,3S)-(+)-Di(p-anisoyl)tartaric acid, (S,S)-Di-p-anisoyltartaric acid, (+)-Di-p-anisoyl-D-tartaric Acid, Dibenzoyl-(+)-P-methoxy-D-tartaric acid, Butanedioic acid, 2,3-bis[(4-methoxybenzoyl)oxy]-, (2S,3S)-, Ruxolitinib Impurity N2, (+)-Bis(4-methoxybenzoyl)-D-tartaric Acid, (2S,3S)-2,3-Bis((4-methoxybenzoyl)oxy)succinicacid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ruxolitinib Impurity-H?

The CAS Registry Number of Ruxolitinib Impurity-H is 191605-10-4. It is also known as Di(+)-(p-anisoyl)-D-tartrate, (2S,3S)-2,3-bis((4-methoxybenzoyl)oxy)succinic acid, (2S,3S)-(+)-Di(p-anisoyl)tartaric acid.

What is the molecular formula and molecular weight of Ruxolitinib Impurity-H?

Ruxolitinib Impurity-H has the molecular formula C20H18O10 and a molecular weight of 418.3 g/mol. Its IUPAC name is (2S,3S)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid.

What is Ruxolitinib Impurity-H used for?

Ruxolitinib Impurity-H is supplied as a characterised reference material related to Ruxolitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ruxolitinib Impurity-H can I order?

We supply Ruxolitinib Impurity-H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ruxolitinib Impurity-H?

Yes. Every lot of Ruxolitinib Impurity-H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ruxolitinib Impurity-H be shipped internationally?

Yes. Ruxolitinib Impurity-H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.