2,4-Di-tert-butyl-6-nitrophenol

Name: 2,4-Di-tert-butyl-6-nitrophenol
Brand: Vaqora Chemicals
SKU: VQ-031343

About 2,4-Di-tert-butyl-6-nitrophenol

Vaqora Chemicals supplies 2,4-Di-tert-butyl-6-nitrophenol, an impurity of Ivacaftor registered under CAS number 20039-94-5. Formula C14H21NO3, molecular weight 251.32 g/mol. Alternative names: 2,4-Bis(tert-butyl)-6-nitrophenol and Phenol, 2,4-bis(1,1-dimethylethyl)-6-nitro-.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Ivacaftor impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2,4-Di-tert-butyl-6-nitrophenol is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ivacaftor

View every impurity, metabolite and intermediate we list for Ivacaftor.

Ivacaftor impurities

Specifications & identifiers

Chemical identifiers
Product name	2,4-Di-tert-butyl-6-nitrophenol
Catalogue No.	VQ-031343
CAS Number	20039-94-5
IUPAC name	2,4-ditert-butyl-6-nitrophenol
Molecular formula	C₁₄H₂₁NO₃
Molecular weight	251.32 g/mol
Exact mass	251.1521
Grade	Reference Standard
HSN code	38229090
InChIKey	GVKJWGRAPDVEMC-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC(=C(C(=C1)[N+](=O)[O-])O)C(C)(C)C
PubChem CID	616897

Physical properties
Physical form	Solid
LogP (XLogP3)	5.3
H-bond donors / acceptors	1 / 3
TPSA	66.1 Å²
Synonyms	2,4-Bis(tert-butyl)-6-nitrophenol, Phenol, 2,4-bis(1,1-dimethylethyl)-6-nitro-, Phenol, 2,4-di-t-butyl-6-nitro-, Phenol,2,4-bis(1,1-dimethylethyl)-6-nitro-, 6-nitro-2,4-di(t-butyl)phenol, 2,4-Bis(2-methyl-2-propanyl)-6-nitrophenol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P264, P264 + P265, P270, P273, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,4-Di-tert-butyl-6-nitrophenol?

The CAS Registry Number of 2,4-Di-tert-butyl-6-nitrophenol is 20039-94-5. It is also known as 2,4-Bis(tert-butyl)-6-nitrophenol, Phenol, 2,4-bis(1,1-dimethylethyl)-6-nitro-, Phenol, 2,4-di-t-butyl-6-nitro-.

What is the molecular formula and molecular weight of 2,4-Di-tert-butyl-6-nitrophenol?

2,4-Di-tert-butyl-6-nitrophenol has the molecular formula C14H21NO3 and a molecular weight of 251.32 g/mol. Its IUPAC name is 2,4-ditert-butyl-6-nitrophenol.

What is 2,4-Di-tert-butyl-6-nitrophenol used for?

2,4-Di-tert-butyl-6-nitrophenol is supplied as a characterised reference material related to Ivacaftor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,4-Di-tert-butyl-6-nitrophenol can I order?

We supply 2,4-Di-tert-butyl-6-nitrophenol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,4-Di-tert-butyl-6-nitrophenol?

Yes. Every lot of 2,4-Di-tert-butyl-6-nitrophenol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,4-Di-tert-butyl-6-nitrophenol be shipped internationally?

Yes. 2,4-Di-tert-butyl-6-nitrophenol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.