Azelastine EP Impurity E

About Azelastine EP Impurity E

Azelastine EP Impurity E is a pharmacopeial impurity of Azelastine carrying the CAS registry number 20526-97-0. Its molecular formula is C15H9ClO2 and its molecular weight is 256.68 g/mol. The IUPAC name is 3-[(4-chlorophenyl)methylidene]-2-benzofuran-1-one. It is also known as 3-(4-Chlorobenzal)phthalide or Azelastine - Impurity E.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Azelastine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Azelastine EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Azelastine

View every impurity, metabolite and intermediate we list for Azelastine.

Azelastine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Azelastine EP Impurity E
Catalogue No.	VQ-021701
CAS Number	20526-97-0
IUPAC name	3-[(4-chlorophenyl)methylidene]-2-benzofuran-1-one
Molecular formula	C₁₅H₉ClO₂
Molecular weight	256.68 g/mol
Exact mass	256.0291
Grade	Reference Standard
HSN code	38229090
InChIKey	OHRFHJYUEWVXBD-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=CC3=CC=C(C=C3)Cl)OC2=O
PubChem CID	89347

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	0 / 2
TPSA	26.3 Å²
Synonyms	3-(4-Chlorobenzal)phthalide, Azelastine EP Impurity E, azelastine USP rc e, Azelastine - Impurity E, 3-(4-chlorobenzylidene)isobenzofuran-1(3H)-one, 3-((4-Chlorophenyl)methylene)phthalide, 1(3H)-Isobenzofuranone, 3-[(4-chlorophenyl)methylene]-, (E/Z)-3-(4-chlorobenzylidene)isobenzofuran-1(3H)-one, 3-[(4-chlorophenyl)methylene]isobenzofuran-1-one, 3-[(4-Chlorophenyl)methylidene]-2-benzofuran-1(3H)-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Azelastine EP Impurity E?

The CAS Registry Number of Azelastine EP Impurity E is 20526-97-0. It is also known as 3-(4-Chlorobenzal)phthalide, Azelastine EP Impurity E, azelastine USP rc e.

What is the molecular formula and molecular weight of Azelastine EP Impurity E?

Azelastine EP Impurity E has the molecular formula C15H9ClO2 and a molecular weight of 256.68 g/mol. Its IUPAC name is 3-[(4-chlorophenyl)methylidene]-2-benzofuran-1-one.

What is Azelastine EP Impurity E used for?

Azelastine EP Impurity E is supplied as a characterised reference material related to Azelastine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Azelastine EP Impurity E can I order?

We supply Azelastine EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Azelastine EP Impurity E?

Yes. Every lot of Azelastine EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Azelastine EP Impurity E be shipped internationally?

Yes. We export Azelastine EP Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.