Simvastatin EP Impurity C

Name: Simvastatin EP Impurity C
Brand: Vaqora Chemicals
SKU: VQ-028034

About Simvastatin EP Impurity C

Listed under CAS 210980-68-0, Simvastatin EP Impurity C is a pharmacopeial impurity of Simvastatin available from Vaqora Chemicals. Its molecular formula is C25H36O4 and its molecular weight is 400.5 g/mol. It is also known as Simvastatin - Impurity C or Anhydro simvastatin.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Simvastatin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Simvastatin EP Impurity C in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Simvastatin

View every impurity, metabolite and intermediate we list for Simvastatin.

Simvastatin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Simvastatin EP Impurity C
Catalogue No.	VQ-028034
CAS Number	210980-68-0
IUPAC name	[(1S,3R,7S,8S,8aR)-3,7-dimethyl-8-[2-[(2R)-6-oxo-2,3-dihydropyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate
Molecular formula	C₂₅H₃₆O₄
Molecular weight	400.5 g/mol
Exact mass	400.2614
Grade	Reference Standard
HSN code	38229090
InChIKey	BIYWBTKPNWCYHM-RLSQPJRHSA-N
SMILES	CCC(C)(C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3CC=CC(=O)O3)C
PubChem CID	58855087

Physical properties
Physical form	Solid
LogP (XLogP3)	5.8
H-bond donors / acceptors	0 / 4
TPSA	52.6 Å²
Synonyms	Simvastatin - Impurity C, Anhydro simvastatin, Dehydrosimvastatin, Anhydro-simvastatin, Simvastatin specified impurity C, Anhydrosimvastatin, Dehydro Simvastatin, Simvastatin Impurity C, Simvastatin Impurity 66, Anhydro Simvastatin (Simvastatin Impurity C)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P233, P260, P261, P264, P270, P271, P272, P273, P280, P284, P301 + P317, P302 + P352, P304 + P340, P318, P319, P321, P330, P333 + P317, P342 + P316, P362 + P364, P391, P403, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Simvastatin EP Impurity C?

The CAS Registry Number of Simvastatin EP Impurity C is 210980-68-0. It is also known as Simvastatin - Impurity C, Anhydro simvastatin, Dehydrosimvastatin.

What is the molecular formula and molecular weight of Simvastatin EP Impurity C?

Simvastatin EP Impurity C has the molecular formula C25H36O4 and a molecular weight of 400.5 g/mol. Its IUPAC name is [(1S,3R,7S,8S,8aR)-3,7-dimethyl-8-[2-[(2R)-6-oxo-2,3-dihydropyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate.

What is Simvastatin EP Impurity C used for?

Simvastatin EP Impurity C is supplied as a characterised reference material related to Simvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Simvastatin EP Impurity C can I order?

We supply Simvastatin EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Simvastatin EP Impurity C?

Yes. Every lot of Simvastatin EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Simvastatin EP Impurity C be shipped internationally?

Yes. Simvastatin EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.