Trimethoprim EP Impurity A

Name: Trimethoprim EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-028539

About Trimethoprim EP Impurity A

Listed under CAS 213745-86-9, Trimethoprim EP Impurity A is a pharmacopeial impurity of Trimethoprim available from Vaqora Chemicals. Formula C15H20N4O3, molecular weight 304.34 g/mol. Systematically, it is named 2-N-methyl-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine. Alternative names: Trimethoprim - Impurity A and 2-Desamino-2-methylamino trimethoprim.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Trimethoprim, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Trimethoprim EP Impurity A is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Trimethoprim

View every impurity, metabolite and intermediate we list for Trimethoprim.

Trimethoprim impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Trimethoprim EP Impurity A
Catalogue No.	VQ-028539
CAS Number	213745-86-9
IUPAC name	2-N-methyl-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
Molecular formula	C₁₅H₂₀N₄O₃
Molecular weight	304.34 g/mol
Exact mass	304.1535
Grade	Reference Standard
HSN code	38229090
InChIKey	LCMRPHMVLYACMM-UHFFFAOYSA-N
SMILES	CNC1=NC=C(C(=N1)N)CC2=CC(=C(C(=C2)OC)OC)OC
PubChem CID	44296584

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	2 / 7
TPSA	91.5 Å²
Synonyms	Trimethoprim - Impurity A, 2-Desamino-2-methylamino trimethoprim, 4-Amino-2-methylamino-5-(3,4,5-trimethoxybenzyl)pyrimidine, 2,4-Pyrimidinediamine, N2-methyl-5-((3,4,5-trimethoxyphenyl)methyl)-, N2-Methyl-5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine, Trimethoprim Impurity A, N2-Methyl Trimethoprim (Impurity), N2-Methyl-5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine, N2-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,4-diamine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trimethoprim EP Impurity A?

The CAS Registry Number of Trimethoprim EP Impurity A is 213745-86-9. It is also known as Trimethoprim - Impurity A, 2-Desamino-2-methylamino trimethoprim, 4-Amino-2-methylamino-5-(3,4,5-trimethoxybenzyl)pyrimidine.

What is the molecular formula and molecular weight of Trimethoprim EP Impurity A?

Trimethoprim EP Impurity A has the molecular formula C15H20N4O3 and a molecular weight of 304.34 g/mol. Its IUPAC name is 2-N-methyl-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine.

What is Trimethoprim EP Impurity A used for?

Trimethoprim EP Impurity A is supplied as a characterised reference material related to Trimethoprim. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trimethoprim EP Impurity A can I order?

We supply Trimethoprim EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trimethoprim EP Impurity A?

Yes. Every lot of Trimethoprim EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trimethoprim EP Impurity A be shipped internationally?

Yes. Trimethoprim EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.